Cargando…

Defining hierarchical protein interaction networks from spectral analysis of bacterial proteomes

Cellular behaviors emerge from layers of molecular interactions: proteins interact to form complexes, pathways, and phenotypes. We show that hierarchical networks of protein interactions can be defined from the statistical pattern of proteome variation measured across thousands of diverse bacteria a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zaydman, Mark A, Little, Alexander S, Haro, Fidel, Aksianiuk, Valeryia, Buchser, William J, DiAntonio, Aaron, Gordon, Jeffrey I, Milbrandt, Jeffrey, Raman, Arjun S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427106/ https://www.ncbi.nlm.nih.gov/pubmed/35976223 http://dx.doi.org/10.7554/eLife.74104

Ejemplares similares

Domain-centric database to uncover structure of minimally characterized viral genomes
por: Bramley, John C., et al.
Publicado: (2020)

Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition
por: Weagley, James S., et al.
Publicado: (2022)

The SARM1 TIR NADase: Mechanistic Similarities to Bacterial Phage Defense and Toxin-Antitoxin Systems
por: DiAntonio, Aaron, et al.
Publicado: (2021)

SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration
por: Ko, Kwang Woo, et al.
Publicado: (2020)

A phytobacterial TIR domain effector manipulates NAD(+) to promote virulence
por: Eastman, Samuel, et al.
Publicado: (2021)

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD(+) depletion
por: Sasaki, Yo, et al.
Publicado: (2016)

Live imaging reveals the cellular events downstream of SARM1 activation
por: Ko, Kwang Woo, et al.
Publicado: (2021)

Spectral analysis of nonlinear elastic shapes
por: Doyle, James F
Publicado: (2020)

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients
por: Bloom, A. Joseph, et al.
Publicado: (2022)

A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model
por: Sato-Yamada, Yurie, et al.
Publicado: (2022)

MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2
por: Walker, Lauren J, et al.
Publicado: (2017)

Complex dimensions of fractal strings and explicit formulas for geometric and spectral zeta-functions
por: Lapidus, M L, et al.
Publicado: (1997)

Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans
por: Kaur, Gurmeet, et al.
Publicado: (2021)

Spectral dynamic causal modeling of mindfulness, mind-wandering, and resting-state in the triple network using fMRI
por: Kim, Hyun-Chul, et al.
Publicado: (2022)

Small Molecule SARM1 Inhibitors Recapitulate the SARM1(−/−) Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate
por: Hughes, Robert O., et al.
Publicado: (2021)

TRPV1 Agonist, Capsaicin, Induces Axon Outgrowth after Injury via Ca(2+)/PKA Signaling
por: Frey, Erin, et al.
Publicado: (2018)

Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy
por: Krus, Kelsey L., et al.
Publicado: (2022)

Decoding violated sensory expectations from the auditory cortex of anaesthetised mice: Hierarchical recurrent neural network depicts separate ‘danger’ and ‘safety’ units
por: O'Reilly, Jamie A., et al.
Publicado: (2022)

Parallel processing, hierarchical transformations, and sensorimotor associations along the ‘where’ pathway
por: Doudlah, Raymond, et al.
Publicado: (2022)

An Experimental Framework for Quantifying Bacterial Tolerance
por: Brauner, Asher, et al.
Publicado: (2017)

Multicolor fluorescence fluctuation spectroscopy in living cells via spectral detection
por: Dunsing, Valentin, et al.
Publicado: (2021)

Contrasting action and posture coding with hierarchical deep neural network models of proprioception
por: Sandbrink, Kai J, et al.
Publicado: (2023)

Gene therapy targeting SARM1 blocks pathological axon degeneration in mice
por: Geisler, Stefanie, et al.
Publicado: (2019)

EEG alpha and pupil diameter reflect endogenous auditory attention switching and listening effort
por: Haro, Stephanie, et al.
Publicado: (2022)

Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis
por: Becker, Mike, et al.
Publicado: (2019)

Hierarchical microphase separation in non-conserved active mixtures
por: Li, Yuting I., et al.
Publicado: (2021)

GlnK Facilitates the Dynamic Regulation of Bacterial Nitrogen Assimilation
por: Gosztolai, Adam, et al.
Publicado: (2017)

Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function
por: Molendijk, Jeffrey, et al.
Publicado: (2022)

Spectral clustering of risk score trajectories stratifies sepsis patients by clinical outcome and interventions received
por: Liu, Ran, et al.
Publicado: (2020)

Defining Information Needs for Public Health Systems and Services Research
por: Buehler, James W.
Publicado: (2014)

Defining host–pathogen interactions employing an artificial intelligence workflow
por: Fisch, Daniel, et al.
Publicado: (2019)

An amalgamation of YOLOv4 and XGBoost for next-gen smart traffic management system
por: Dave, Pritul, et al.
Publicado: (2021)

A hierarchical model for external electrical control of an insect, accounting for inter-individual variation of muscle force properties
por: Owaki, Dai, et al.
Publicado: (2023)

Distinct developmental and degenerative functions of SARM1 require NAD(+) hydrolase activity
por: Brace, E. J., et al.
Publicado: (2022)

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment
por: Byron, Adam, et al.
Publicado: (2012)

A Modular View of the Diversity of Cell-Density-Encoding Schemes in Bacterial Quorum-Sensing Systems
por: Drees, Bastian, et al.
Publicado: (2014)

Proteomics and Network Analyses Reveal Inhibition of Akt‐mTOR Signaling in CD4(+) T Cells by Mycobacterium tuberculosis Mannose‐Capped Lipoarabinomannan
por: Karim, Ahmad F., et al.
Publicado: (2017)

Short-Wavelength Sensitive Cone (S-cone) Testing as an Outcome Measure for NR2E3 Clinical Treatment Trials
por: Roman, Alejandro J., et al.
Publicado: (2019)

A sensorimotor model shows why a spectral jamming avoidance response does not help bats deal with jamming
por: Mazar, Omer, et al.
Publicado: (2020)

Rapid, High-Throughput Tracking of Bacterial Motility in 3D via Phase-Contrast Holographic Video Microscopy
por: Cheong, Fook Chiong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_oq3ltcq3fa3gqud610r10vog61