Cargando…

Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil

This study aimed to estimate the prevalence of infection by the hepatitis B virus (HBV) and hepatitis C virus (HCV) in people infected by the human immunodeficiency virus (HIV) and analyze sociodemographic and behavioral factors associated with such co-infection. A cross-section study was performed...

Descripción completa

Detalles Bibliográficos
Autores principales: Brandão, Natália Alberto Alves, Pfrimer, Irmtraut Araci Hoffmann, Martelli, Celina Maria Turchi, Turchi, Marília Dalva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427459/
https://www.ncbi.nlm.nih.gov/pubmed/25766773
http://dx.doi.org/10.1016/j.bjid.2015.02.001
_version_ 1784778907717730304
author Brandão, Natália Alberto Alves
Pfrimer, Irmtraut Araci Hoffmann
Martelli, Celina Maria Turchi
Turchi, Marília Dalva
author_facet Brandão, Natália Alberto Alves
Pfrimer, Irmtraut Araci Hoffmann
Martelli, Celina Maria Turchi
Turchi, Marília Dalva
author_sort Brandão, Natália Alberto Alves
collection PubMed
description This study aimed to estimate the prevalence of infection by the hepatitis B virus (HBV) and hepatitis C virus (HCV) in people infected by the human immunodeficiency virus (HIV) and analyze sociodemographic and behavioral factors associated with such co-infection. A cross-section study was performed in 495 individuals treated at a public center in the city of Goiânia. Participants were interviewed and blood collected for evaluation of serological and molecular markers for HBV and HCV. The rate of exposure to HBV was 33.5% (95% CI 29.4–37.9). Nineteen patients (3.8%) were diagnosed as HBV carriers, of whom 68.4% were HBV DNA positive. The prevalence of anti-HCV was 9.7% (95% CI 7.3–12.7). Genotype 1a was identified in 72.7% of the PCR samples positive for HCV. Co-infection by all three viruses was 4.4% (95% CI 2.9–6.8). Being, male, aged ≥40 years, history of sexually transmitted disease (STD), and having homosexual practices were independently associated with the presence of markers of HBV exposure. A history of injectable drugs use and STDs showed association with HCV seropositivity. Approximately 50% of participants were not aware of their HBV and HCV serostatus. The results obtained may contribute to assess the burden of viral hepatitis in people living with HIV and to guiding preventive measures for more vulnerable groups.
format Online
Article
Text
id pubmed-9427459
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-94274592022-09-01 Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil Brandão, Natália Alberto Alves Pfrimer, Irmtraut Araci Hoffmann Martelli, Celina Maria Turchi Turchi, Marília Dalva Braz J Infect Dis Brief Communication This study aimed to estimate the prevalence of infection by the hepatitis B virus (HBV) and hepatitis C virus (HCV) in people infected by the human immunodeficiency virus (HIV) and analyze sociodemographic and behavioral factors associated with such co-infection. A cross-section study was performed in 495 individuals treated at a public center in the city of Goiânia. Participants were interviewed and blood collected for evaluation of serological and molecular markers for HBV and HCV. The rate of exposure to HBV was 33.5% (95% CI 29.4–37.9). Nineteen patients (3.8%) were diagnosed as HBV carriers, of whom 68.4% were HBV DNA positive. The prevalence of anti-HCV was 9.7% (95% CI 7.3–12.7). Genotype 1a was identified in 72.7% of the PCR samples positive for HCV. Co-infection by all three viruses was 4.4% (95% CI 2.9–6.8). Being, male, aged ≥40 years, history of sexually transmitted disease (STD), and having homosexual practices were independently associated with the presence of markers of HBV exposure. A history of injectable drugs use and STDs showed association with HCV seropositivity. Approximately 50% of participants were not aware of their HBV and HCV serostatus. The results obtained may contribute to assess the burden of viral hepatitis in people living with HIV and to guiding preventive measures for more vulnerable groups. Elsevier 2015-03-09 /pmc/articles/PMC9427459/ /pubmed/25766773 http://dx.doi.org/10.1016/j.bjid.2015.02.001 Text en © 2015 Elsevier Editora Ltda. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Brief Communication
Brandão, Natália Alberto Alves
Pfrimer, Irmtraut Araci Hoffmann
Martelli, Celina Maria Turchi
Turchi, Marília Dalva
Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
title Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
title_full Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
title_fullStr Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
title_full_unstemmed Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
title_short Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
title_sort prevalence of hepatitis b and c infection and associated factors in people living with hiv in midwestern brazil
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427459/
https://www.ncbi.nlm.nih.gov/pubmed/25766773
http://dx.doi.org/10.1016/j.bjid.2015.02.001
work_keys_str_mv AT brandaonataliaalbertoalves prevalenceofhepatitisbandcinfectionandassociatedfactorsinpeoplelivingwithhivinmidwesternbrazil
AT pfrimerirmtrautaracihoffmann prevalenceofhepatitisbandcinfectionandassociatedfactorsinpeoplelivingwithhivinmidwesternbrazil
AT martellicelinamariaturchi prevalenceofhepatitisbandcinfectionandassociatedfactorsinpeoplelivingwithhivinmidwesternbrazil
AT turchimariliadalva prevalenceofhepatitisbandcinfectionandassociatedfactorsinpeoplelivingwithhivinmidwesternbrazil