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Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil
This study aimed to estimate the prevalence of infection by the hepatitis B virus (HBV) and hepatitis C virus (HCV) in people infected by the human immunodeficiency virus (HIV) and analyze sociodemographic and behavioral factors associated with such co-infection. A cross-section study was performed...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427459/ https://www.ncbi.nlm.nih.gov/pubmed/25766773 http://dx.doi.org/10.1016/j.bjid.2015.02.001 |
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author | Brandão, Natália Alberto Alves Pfrimer, Irmtraut Araci Hoffmann Martelli, Celina Maria Turchi Turchi, Marília Dalva |
author_facet | Brandão, Natália Alberto Alves Pfrimer, Irmtraut Araci Hoffmann Martelli, Celina Maria Turchi Turchi, Marília Dalva |
author_sort | Brandão, Natália Alberto Alves |
collection | PubMed |
description | This study aimed to estimate the prevalence of infection by the hepatitis B virus (HBV) and hepatitis C virus (HCV) in people infected by the human immunodeficiency virus (HIV) and analyze sociodemographic and behavioral factors associated with such co-infection. A cross-section study was performed in 495 individuals treated at a public center in the city of Goiânia. Participants were interviewed and blood collected for evaluation of serological and molecular markers for HBV and HCV. The rate of exposure to HBV was 33.5% (95% CI 29.4–37.9). Nineteen patients (3.8%) were diagnosed as HBV carriers, of whom 68.4% were HBV DNA positive. The prevalence of anti-HCV was 9.7% (95% CI 7.3–12.7). Genotype 1a was identified in 72.7% of the PCR samples positive for HCV. Co-infection by all three viruses was 4.4% (95% CI 2.9–6.8). Being, male, aged ≥40 years, history of sexually transmitted disease (STD), and having homosexual practices were independently associated with the presence of markers of HBV exposure. A history of injectable drugs use and STDs showed association with HCV seropositivity. Approximately 50% of participants were not aware of their HBV and HCV serostatus. The results obtained may contribute to assess the burden of viral hepatitis in people living with HIV and to guiding preventive measures for more vulnerable groups. |
format | Online Article Text |
id | pubmed-9427459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94274592022-09-01 Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil Brandão, Natália Alberto Alves Pfrimer, Irmtraut Araci Hoffmann Martelli, Celina Maria Turchi Turchi, Marília Dalva Braz J Infect Dis Brief Communication This study aimed to estimate the prevalence of infection by the hepatitis B virus (HBV) and hepatitis C virus (HCV) in people infected by the human immunodeficiency virus (HIV) and analyze sociodemographic and behavioral factors associated with such co-infection. A cross-section study was performed in 495 individuals treated at a public center in the city of Goiânia. Participants were interviewed and blood collected for evaluation of serological and molecular markers for HBV and HCV. The rate of exposure to HBV was 33.5% (95% CI 29.4–37.9). Nineteen patients (3.8%) were diagnosed as HBV carriers, of whom 68.4% were HBV DNA positive. The prevalence of anti-HCV was 9.7% (95% CI 7.3–12.7). Genotype 1a was identified in 72.7% of the PCR samples positive for HCV. Co-infection by all three viruses was 4.4% (95% CI 2.9–6.8). Being, male, aged ≥40 years, history of sexually transmitted disease (STD), and having homosexual practices were independently associated with the presence of markers of HBV exposure. A history of injectable drugs use and STDs showed association with HCV seropositivity. Approximately 50% of participants were not aware of their HBV and HCV serostatus. The results obtained may contribute to assess the burden of viral hepatitis in people living with HIV and to guiding preventive measures for more vulnerable groups. Elsevier 2015-03-09 /pmc/articles/PMC9427459/ /pubmed/25766773 http://dx.doi.org/10.1016/j.bjid.2015.02.001 Text en © 2015 Elsevier Editora Ltda. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Brief Communication Brandão, Natália Alberto Alves Pfrimer, Irmtraut Araci Hoffmann Martelli, Celina Maria Turchi Turchi, Marília Dalva Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil |
title | Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil |
title_full | Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil |
title_fullStr | Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil |
title_full_unstemmed | Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil |
title_short | Prevalence of hepatitis B and C infection and associated factors in people living with HIV in Midwestern Brazil |
title_sort | prevalence of hepatitis b and c infection and associated factors in people living with hiv in midwestern brazil |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427459/ https://www.ncbi.nlm.nih.gov/pubmed/25766773 http://dx.doi.org/10.1016/j.bjid.2015.02.001 |
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