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The role of microRNAs in enteroviral infections
The genus Enterovirus, a member of the Picornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427576/ https://www.ncbi.nlm.nih.gov/pubmed/26342975 http://dx.doi.org/10.1016/j.bjid.2015.06.011 |
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author | Wu, Jing Shen, Li Chen, Jianguo Xu, Huaxi Mao, Lingxiang |
author_facet | Wu, Jing Shen, Li Chen, Jianguo Xu, Huaxi Mao, Lingxiang |
author_sort | Wu, Jing |
collection | PubMed |
description | The genus Enterovirus, a member of the Picornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators of gene expression. Recent studies found that MicroRNAs play a significant role in the infection of Enterovirus, such as enterovirus 71, coxsackievirus B3 and other Enterovirus. Enteroviral infection can alter the expression of cellular MicroRNAs, and cellular MicroRNAs can modulate viral pathogenesis and replication by regulating the expression level of viral or host's genes. Herein, this review summarizes the role of MicroRNAs in enteroviral infection. |
format | Online Article Text |
id | pubmed-9427576 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94275762022-09-01 The role of microRNAs in enteroviral infections Wu, Jing Shen, Li Chen, Jianguo Xu, Huaxi Mao, Lingxiang Braz J Infect Dis Review Article The genus Enterovirus, a member of the Picornavirus family, are RNA viruses that can cause poliomyelitis, hand-food-mouth disease, viral meningitis or meningoencephalitis, viral myocarditis and so on. MicroRNAs are a class of highly conserved, small noncoding RNAs recognized as important regulators of gene expression. Recent studies found that MicroRNAs play a significant role in the infection of Enterovirus, such as enterovirus 71, coxsackievirus B3 and other Enterovirus. Enteroviral infection can alter the expression of cellular MicroRNAs, and cellular MicroRNAs can modulate viral pathogenesis and replication by regulating the expression level of viral or host's genes. Herein, this review summarizes the role of MicroRNAs in enteroviral infection. Elsevier 2015-09-03 /pmc/articles/PMC9427576/ /pubmed/26342975 http://dx.doi.org/10.1016/j.bjid.2015.06.011 Text en © 2015 Elsevier Editora Ltda. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Wu, Jing Shen, Li Chen, Jianguo Xu, Huaxi Mao, Lingxiang The role of microRNAs in enteroviral infections |
title | The role of microRNAs in enteroviral infections |
title_full | The role of microRNAs in enteroviral infections |
title_fullStr | The role of microRNAs in enteroviral infections |
title_full_unstemmed | The role of microRNAs in enteroviral infections |
title_short | The role of microRNAs in enteroviral infections |
title_sort | role of micrornas in enteroviral infections |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427576/ https://www.ncbi.nlm.nih.gov/pubmed/26342975 http://dx.doi.org/10.1016/j.bjid.2015.06.011 |
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