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Therapeutics for rheumatic fever and rheumatic heart disease

The goals of acute rheumatic fever therapy are to relieve symptoms, mitigate cardiac valve damage and eradicate streptococcal infection. Preventing future recurrences requires long-term secondary antibiotic prophylaxis and ongoing prevention of Streptococcus pyogenes (group A streptococcus) infectio...

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Autores principales: Ralph, Anna P, Currie, Bart J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: NPS MedicineWise 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427630/
https://www.ncbi.nlm.nih.gov/pubmed/36110174
http://dx.doi.org/10.18773/austprescr.2022.034
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author Ralph, Anna P
Currie, Bart J
author_facet Ralph, Anna P
Currie, Bart J
author_sort Ralph, Anna P
collection PubMed
description The goals of acute rheumatic fever therapy are to relieve symptoms, mitigate cardiac valve damage and eradicate streptococcal infection. Preventing future recurrences requires long-term secondary antibiotic prophylaxis and ongoing prevention of Streptococcus pyogenes (group A streptococcus) infections The recommended regimen for secondary prophylaxis comprises benzathine benzylpenicillin G intramuscular injections every four weeks. For patients with non-severe or immediate penicillin hypersensitivity, use erythromycin orally twice daily The goals of therapy for rheumatic heart disease are to prevent progression and optimise cardiac function. Secondary antibiotic prophylaxis can reduce the long-term severity of rheumatic heart disease Patients with rheumatic heart disease, including those receiving benzathine benzylpenicillin G prophylaxis, should receive amoxicillin prophylaxis before undergoing high-risk dental or surgical procedures. If they have recently been treated with a course of penicillin or amoxicillin, or have immediate penicillin hypersensitivity, clindamycin is recommended
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spelling pubmed-94276302022-09-14 Therapeutics for rheumatic fever and rheumatic heart disease Ralph, Anna P Currie, Bart J Aust Prescr Article The goals of acute rheumatic fever therapy are to relieve symptoms, mitigate cardiac valve damage and eradicate streptococcal infection. Preventing future recurrences requires long-term secondary antibiotic prophylaxis and ongoing prevention of Streptococcus pyogenes (group A streptococcus) infections The recommended regimen for secondary prophylaxis comprises benzathine benzylpenicillin G intramuscular injections every four weeks. For patients with non-severe or immediate penicillin hypersensitivity, use erythromycin orally twice daily The goals of therapy for rheumatic heart disease are to prevent progression and optimise cardiac function. Secondary antibiotic prophylaxis can reduce the long-term severity of rheumatic heart disease Patients with rheumatic heart disease, including those receiving benzathine benzylpenicillin G prophylaxis, should receive amoxicillin prophylaxis before undergoing high-risk dental or surgical procedures. If they have recently been treated with a course of penicillin or amoxicillin, or have immediate penicillin hypersensitivity, clindamycin is recommended NPS MedicineWise 2022-08-01 2022-08 /pmc/articles/PMC9427630/ /pubmed/36110174 http://dx.doi.org/10.18773/austprescr.2022.034 Text en (c) NPS MedicineWise https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License.
spellingShingle Article
Ralph, Anna P
Currie, Bart J
Therapeutics for rheumatic fever and rheumatic heart disease
title Therapeutics for rheumatic fever and rheumatic heart disease
title_full Therapeutics for rheumatic fever and rheumatic heart disease
title_fullStr Therapeutics for rheumatic fever and rheumatic heart disease
title_full_unstemmed Therapeutics for rheumatic fever and rheumatic heart disease
title_short Therapeutics for rheumatic fever and rheumatic heart disease
title_sort therapeutics for rheumatic fever and rheumatic heart disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427630/
https://www.ncbi.nlm.nih.gov/pubmed/36110174
http://dx.doi.org/10.18773/austprescr.2022.034
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