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Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study

Evaluating the outcomes of tuberculosis treatment and understanding the specific reasons for unfavorable treatment outcome are important in evaluating the effectiveness of tuberculosis control program. A retrospective study was conducted to assess tuberculosis treatment outcomes and associated facto...

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Autores principales: Zenebe, Tizazu, Tefera, Ermias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427637/
https://www.ncbi.nlm.nih.gov/pubmed/27553661
http://dx.doi.org/10.1016/j.bjid.2016.07.012
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author Zenebe, Tizazu
Tefera, Ermias
author_facet Zenebe, Tizazu
Tefera, Ermias
author_sort Zenebe, Tizazu
collection PubMed
description Evaluating the outcomes of tuberculosis treatment and understanding the specific reasons for unfavorable treatment outcome are important in evaluating the effectiveness of tuberculosis control program. A retrospective study was conducted to assess tuberculosis treatment outcomes and associated factors among smear positive pulmonary tuberculosis patients in zone-one health facilities of Afar regional state, Ethiopia. A total of 380 smear positive pulmonary tuberculosis patients’ registration book recorded with complete information from Jan 2011 to Dec 2013 were analyzed. Of 380 patients included in the analysis, 238 were male and 142 female with mean age of 30.7. Overall treatment outcome were 128 (33.7%) cured, 192 (50.2%) completed, 17 (4.5%) died, 1 (0.3%) treatment failure, 34 (8.9%) default and 8 (2.1%) transfer out. Treatment success rate was 81.8%. There was statistically significance association between age (p-value = 0.000), sex (p-value = 0.018), HIV status (p-value = 0.000), four week attendance (p-value = 0.000), sputum follow up test (p-value = 0.000), and treatment outcome year (p-value = 0.000), and treatment success (p-value = 0.000). Treatment success rate almost reached to the WHO targets although yet need to work a lot for fulfillment of global targets. Regular four week attendance in continuation phase and doing follow up sputum test with unsuccessful outcome for smear positive tuberculosis patient were vital.
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spelling pubmed-94276372022-09-01 Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study Zenebe, Tizazu Tefera, Ermias Braz J Infect Dis Brief Communication Evaluating the outcomes of tuberculosis treatment and understanding the specific reasons for unfavorable treatment outcome are important in evaluating the effectiveness of tuberculosis control program. A retrospective study was conducted to assess tuberculosis treatment outcomes and associated factors among smear positive pulmonary tuberculosis patients in zone-one health facilities of Afar regional state, Ethiopia. A total of 380 smear positive pulmonary tuberculosis patients’ registration book recorded with complete information from Jan 2011 to Dec 2013 were analyzed. Of 380 patients included in the analysis, 238 were male and 142 female with mean age of 30.7. Overall treatment outcome were 128 (33.7%) cured, 192 (50.2%) completed, 17 (4.5%) died, 1 (0.3%) treatment failure, 34 (8.9%) default and 8 (2.1%) transfer out. Treatment success rate was 81.8%. There was statistically significance association between age (p-value = 0.000), sex (p-value = 0.018), HIV status (p-value = 0.000), four week attendance (p-value = 0.000), sputum follow up test (p-value = 0.000), and treatment outcome year (p-value = 0.000), and treatment success (p-value = 0.000). Treatment success rate almost reached to the WHO targets although yet need to work a lot for fulfillment of global targets. Regular four week attendance in continuation phase and doing follow up sputum test with unsuccessful outcome for smear positive tuberculosis patient were vital. Elsevier 2016-08-21 /pmc/articles/PMC9427637/ /pubmed/27553661 http://dx.doi.org/10.1016/j.bjid.2016.07.012 Text en © 2016 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Brief Communication
Zenebe, Tizazu
Tefera, Ermias
Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study
title Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study
title_full Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study
title_fullStr Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study
title_full_unstemmed Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study
title_short Tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in Afar, Eastern Ethiopia: a retrospective study
title_sort tuberculosis treatment outcome and associated factors among smear-positive pulmonary tuberculosis patients in afar, eastern ethiopia: a retrospective study
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427637/
https://www.ncbi.nlm.nih.gov/pubmed/27553661
http://dx.doi.org/10.1016/j.bjid.2016.07.012
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