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Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)

INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was cond...

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Autores principales: Santos, Dislene N. dos, Santos, Kionna O.B., Paixão, Alaí B., Andrade, Rosana Cristina P. de, Costa, Davi T., S-Martin, Daniel L., Sá, Katia N., Baptista, Abrahão F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427659/
https://www.ncbi.nlm.nih.gov/pubmed/28011062
http://dx.doi.org/10.1016/j.bjid.2016.11.008
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author Santos, Dislene N. dos
Santos, Kionna O.B.
Paixão, Alaí B.
Andrade, Rosana Cristina P. de
Costa, Davi T.
S-Martin, Daniel L.
Sá, Katia N.
Baptista, Abrahão F.
author_facet Santos, Dislene N. dos
Santos, Kionna O.B.
Paixão, Alaí B.
Andrade, Rosana Cristina P. de
Costa, Davi T.
S-Martin, Daniel L.
Sá, Katia N.
Baptista, Abrahão F.
author_sort Santos, Dislene N. dos
collection PubMed
description INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was conducted in a reference center for treatment of patients infected with HTLV-1 in Salvador, Bahia, Brazil. The study included individuals infected with HTLV-1, over 18 years, and excluded those with difficulty to respond the pain protocol. Data on sociodemographic, health behavior, and clinical characteristics were collected in a standardized way. The prevalence ratio (PR) of pain is described, as well as the factors independently associated with the presence of pain, which were assessed by multiple logistic regression. RESULTS: A total of 142 individuals were included in the study, mostly female (62.7%), aged 20–64 years (73.2%), married (61.3%), with less than eight years of education (54.2%), and with a steady income (79.6%). Multivariate analysis showed that being symptomatic for HTLV-1 – sensory manifestations, erectile dysfunction, overactive bladder, and/or HAM/TSP (PR = 1.21, 95% CI: 1.05 to 1.38), self-medication (PR = 1.29, 95% CI: 1.08–1.53), physiotherapy (PR = 1.15, 95% CI: 1.02–1.28), and depression (PR = 1.14, 95% CI: 1.01–1.29) were associated with an increased likelihood of presenting pain. On the other hand, physical activity (PR = 0.79, 95% CI: 0.67–0.93) and religious practice (PR = 0.83, 95% CI: 0.72–0.95) were associated with a decreased likelihood of having pain. CONCLUSION: The use of self-medication, physiotherapy and the presence of depression are independently associated with neurological symptoms in HTLV-1 infected patients. Religious practice and physical activity are both protective for the development of pain.
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spelling pubmed-94276592022-09-01 Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) Santos, Dislene N. dos Santos, Kionna O.B. Paixão, Alaí B. Andrade, Rosana Cristina P. de Costa, Davi T. S-Martin, Daniel L. Sá, Katia N. Baptista, Abrahão F. Braz J Infect Dis Original Article INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was conducted in a reference center for treatment of patients infected with HTLV-1 in Salvador, Bahia, Brazil. The study included individuals infected with HTLV-1, over 18 years, and excluded those with difficulty to respond the pain protocol. Data on sociodemographic, health behavior, and clinical characteristics were collected in a standardized way. The prevalence ratio (PR) of pain is described, as well as the factors independently associated with the presence of pain, which were assessed by multiple logistic regression. RESULTS: A total of 142 individuals were included in the study, mostly female (62.7%), aged 20–64 years (73.2%), married (61.3%), with less than eight years of education (54.2%), and with a steady income (79.6%). Multivariate analysis showed that being symptomatic for HTLV-1 – sensory manifestations, erectile dysfunction, overactive bladder, and/or HAM/TSP (PR = 1.21, 95% CI: 1.05 to 1.38), self-medication (PR = 1.29, 95% CI: 1.08–1.53), physiotherapy (PR = 1.15, 95% CI: 1.02–1.28), and depression (PR = 1.14, 95% CI: 1.01–1.29) were associated with an increased likelihood of presenting pain. On the other hand, physical activity (PR = 0.79, 95% CI: 0.67–0.93) and religious practice (PR = 0.83, 95% CI: 0.72–0.95) were associated with a decreased likelihood of having pain. CONCLUSION: The use of self-medication, physiotherapy and the presence of depression are independently associated with neurological symptoms in HTLV-1 infected patients. Religious practice and physical activity are both protective for the development of pain. Elsevier 2016-12-21 /pmc/articles/PMC9427659/ /pubmed/28011062 http://dx.doi.org/10.1016/j.bjid.2016.11.008 Text en © 2016 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Santos, Dislene N. dos
Santos, Kionna O.B.
Paixão, Alaí B.
Andrade, Rosana Cristina P. de
Costa, Davi T.
S-Martin, Daniel L.
Sá, Katia N.
Baptista, Abrahão F.
Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
title Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
title_full Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
title_fullStr Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
title_full_unstemmed Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
title_short Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
title_sort factors associated with pain in individuals infected by human t-cell lymphotropic virus type 1 (htlv-1)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427659/
https://www.ncbi.nlm.nih.gov/pubmed/28011062
http://dx.doi.org/10.1016/j.bjid.2016.11.008
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