Cargando…
Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1)
INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was cond...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427659/ https://www.ncbi.nlm.nih.gov/pubmed/28011062 http://dx.doi.org/10.1016/j.bjid.2016.11.008 |
_version_ | 1784778956353830912 |
---|---|
author | Santos, Dislene N. dos Santos, Kionna O.B. Paixão, Alaí B. Andrade, Rosana Cristina P. de Costa, Davi T. S-Martin, Daniel L. Sá, Katia N. Baptista, Abrahão F. |
author_facet | Santos, Dislene N. dos Santos, Kionna O.B. Paixão, Alaí B. Andrade, Rosana Cristina P. de Costa, Davi T. S-Martin, Daniel L. Sá, Katia N. Baptista, Abrahão F. |
author_sort | Santos, Dislene N. dos |
collection | PubMed |
description | INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was conducted in a reference center for treatment of patients infected with HTLV-1 in Salvador, Bahia, Brazil. The study included individuals infected with HTLV-1, over 18 years, and excluded those with difficulty to respond the pain protocol. Data on sociodemographic, health behavior, and clinical characteristics were collected in a standardized way. The prevalence ratio (PR) of pain is described, as well as the factors independently associated with the presence of pain, which were assessed by multiple logistic regression. RESULTS: A total of 142 individuals were included in the study, mostly female (62.7%), aged 20–64 years (73.2%), married (61.3%), with less than eight years of education (54.2%), and with a steady income (79.6%). Multivariate analysis showed that being symptomatic for HTLV-1 – sensory manifestations, erectile dysfunction, overactive bladder, and/or HAM/TSP (PR = 1.21, 95% CI: 1.05 to 1.38), self-medication (PR = 1.29, 95% CI: 1.08–1.53), physiotherapy (PR = 1.15, 95% CI: 1.02–1.28), and depression (PR = 1.14, 95% CI: 1.01–1.29) were associated with an increased likelihood of presenting pain. On the other hand, physical activity (PR = 0.79, 95% CI: 0.67–0.93) and religious practice (PR = 0.83, 95% CI: 0.72–0.95) were associated with a decreased likelihood of having pain. CONCLUSION: The use of self-medication, physiotherapy and the presence of depression are independently associated with neurological symptoms in HTLV-1 infected patients. Religious practice and physical activity are both protective for the development of pain. |
format | Online Article Text |
id | pubmed-9427659 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-94276592022-09-01 Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) Santos, Dislene N. dos Santos, Kionna O.B. Paixão, Alaí B. Andrade, Rosana Cristina P. de Costa, Davi T. S-Martin, Daniel L. Sá, Katia N. Baptista, Abrahão F. Braz J Infect Dis Original Article INTRODUCTION: Despite the high prevalence of chronic pain in individuals infected with HTLV-1, predictive and protective factors for its development are still unclear. OBJECTIVE: To identify factors associated with chronic pain in individuals with HTLV-1. METHODS: This cross-sectional study was conducted in a reference center for treatment of patients infected with HTLV-1 in Salvador, Bahia, Brazil. The study included individuals infected with HTLV-1, over 18 years, and excluded those with difficulty to respond the pain protocol. Data on sociodemographic, health behavior, and clinical characteristics were collected in a standardized way. The prevalence ratio (PR) of pain is described, as well as the factors independently associated with the presence of pain, which were assessed by multiple logistic regression. RESULTS: A total of 142 individuals were included in the study, mostly female (62.7%), aged 20–64 years (73.2%), married (61.3%), with less than eight years of education (54.2%), and with a steady income (79.6%). Multivariate analysis showed that being symptomatic for HTLV-1 – sensory manifestations, erectile dysfunction, overactive bladder, and/or HAM/TSP (PR = 1.21, 95% CI: 1.05 to 1.38), self-medication (PR = 1.29, 95% CI: 1.08–1.53), physiotherapy (PR = 1.15, 95% CI: 1.02–1.28), and depression (PR = 1.14, 95% CI: 1.01–1.29) were associated with an increased likelihood of presenting pain. On the other hand, physical activity (PR = 0.79, 95% CI: 0.67–0.93) and religious practice (PR = 0.83, 95% CI: 0.72–0.95) were associated with a decreased likelihood of having pain. CONCLUSION: The use of self-medication, physiotherapy and the presence of depression are independently associated with neurological symptoms in HTLV-1 infected patients. Religious practice and physical activity are both protective for the development of pain. Elsevier 2016-12-21 /pmc/articles/PMC9427659/ /pubmed/28011062 http://dx.doi.org/10.1016/j.bjid.2016.11.008 Text en © 2016 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Santos, Dislene N. dos Santos, Kionna O.B. Paixão, Alaí B. Andrade, Rosana Cristina P. de Costa, Davi T. S-Martin, Daniel L. Sá, Katia N. Baptista, Abrahão F. Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) |
title | Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) |
title_full | Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) |
title_fullStr | Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) |
title_full_unstemmed | Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) |
title_short | Factors associated with pain in individuals infected by human T-cell lymphotropic virus type 1 (HTLV-1) |
title_sort | factors associated with pain in individuals infected by human t-cell lymphotropic virus type 1 (htlv-1) |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427659/ https://www.ncbi.nlm.nih.gov/pubmed/28011062 http://dx.doi.org/10.1016/j.bjid.2016.11.008 |
work_keys_str_mv | AT santosdislenendos factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT santoskionnaob factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT paixaoalaib factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT andraderosanacristinapde factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT costadavit factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT smartindaniell factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT sakatian factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 AT baptistaabrahaof factorsassociatedwithpaininindividualsinfectedbyhumantcelllymphotropicvirustype1htlv1 |