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Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Aedes aegypti has evolved to become an efficient vector for arboviruses but the mechanisms of host-pathogen tolerance are unknown. Immunoreceptor Toll and its ligand Spaetzle have undergone duplication which may allow neofunctionalization and adaptation. Here we present cryo-EM structures and biophy...

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Detalles Bibliográficos
Autores principales:	Saucereau, Yoann, Wilson, Thomas H., Tang, Matthew C. K., Moncrieffe, Martin C., Hardwick, Steven W., Chirgadze, Dimitri Y., Soares, Sandro G., Marcaida, Maria Jose, Gay, Nicholas J., Gangloff, Monique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427763/ https://www.ncbi.nlm.nih.gov/pubmed/36042238 http://dx.doi.org/10.1038/s41467-022-32690-6

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