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Homodimerized cytoplasmic domain of PD-L1 regulates its complex glycosylation in living cells

Whether membrane-anchored PD-L1 homodimerizes in living cells is controversial. The biological significance of the homodimer waits to be expeditiously explored. However, characterization of the membrane-anchored full-length PD-L1 homodimer is challenging, and unconventional approaches are needed. By...

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Detalles Bibliográficos
Autores principales: Zhou, Li, Chai, Fangni, He, Yong, Zhou, Zhihui, Guo, Shupan, Li, Pan, Sun, Qi, Zu, Xueyin, Liu, Xin, Huang, Qin, Zhong, Yanping, Zhou, Aolan, Wang, Xueyun, Ren, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427764/
https://www.ncbi.nlm.nih.gov/pubmed/36042378
http://dx.doi.org/10.1038/s42003-022-03845-4