Activation of recombinational repair in Ewing sarcoma cells carrying EWS-FLI1 fusion gene by chromosome translocation

Chromosome translocation (TL) is an important mode of genomic changes underlying human tumorigenesis, the detailed mechanisms of which are, however, still not well understood. The two major modalities of DNA double strand break repair, i.e. homologous recombination (HR) and non-homologous end-joinin...

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Detalles Bibliográficos
Autores principales: Tanaka, Kazuhiro, Suzuki, Keiji, Miyashita, Kaname, Wakasa, Kentaro, Kawano, Masanori, Nakatsu, Yoshimichi, Tsumura, Hiroshi, Yoshida, Mitsuaki A., Oda, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427769/
https://www.ncbi.nlm.nih.gov/pubmed/36042341
http://dx.doi.org/10.1038/s41598-022-19164-x

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