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Mycobacterium tuberculosis complex bacteremia among HIV and non-HIV patients in a Mexican tertiary care center

OBJECTIVES: To determine the factors associated with Mycobacterium tuberculosis complex-positive blood culture. METHODS: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015. RESULTS: We reviewed medical records of 533 patients with culture-proven tuber...

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Detalles Bibliográficos
Autores principales: Tamez-Torres, Karla Maria, Torres-Gonzalez, Pedro, Cervera-Hernandez, Miguel E., Chavez-Mazari, Barbara, Barrientos-Flores, Corazon de Jesus, Bobadilla-del-Valle, Miriam, Ponce-de-Leon, Alfredo, Sifuentes-Osornio, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427807/
https://www.ncbi.nlm.nih.gov/pubmed/30389350
http://dx.doi.org/10.1016/j.bjid.2018.10.274
Descripción
Sumario:OBJECTIVES: To determine the factors associated with Mycobacterium tuberculosis complex-positive blood culture. METHODS: Case-control study. Sociodemographic, clinical and laboratory data were collected from 2000 to 2015. RESULTS: We reviewed medical records of 533 patients with culture-proven tuberculosis, of whom 27.2% (145/533) had blood culture available. Patients with mycobacteremia presented more frequently with abdominal tuberculosis, body mass index <18 kg/m(2), and had lower hemoglobin and albumin levels. No differences were observed regarding HIV status. CONCLUSIONS: Few studies have reported on the characteristics associated with Mycobacterium tuberculosis complex bacteremia, especially among Human Immunodeficiency Virus-negative patients. Out of 145 tuberculosis-infected patients with blood culture results available, 21 turned out positive. Anemia, hypoalbuminemia, and a body mass index < 18 kg/m(2) were associated with mycobacteremia.