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Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA

Human mitochondrial gene expression relies on the specific recognition and aminoacylation of mitochondrial tRNAs (mtRNAs) by nuclear-encoded mitochondrial aminoacyl-tRNA synthetases (mt-aaRSs). Despite their essential role in cellular energy homeostasis, strong mutation pressure and genetic drift ha...

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Detalles Bibliográficos
Autores principales:	Kuhle, Bernhard, Hirschi, Marscha, Doerfel, Lili K., Lander, Gabriel C., Schimmel, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427863/ https://www.ncbi.nlm.nih.gov/pubmed/36042193 http://dx.doi.org/10.1038/s41467-022-32544-1

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