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Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes

BACKGROUND: The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year. METHODS: Data were obtained from the Norwegian Registry for...

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Autores principales: Johansen, Tonje Okkenhaug, Vangen-Lønne, Vetle, Holmberg, Siril T., Salvesen, Øyvind O., Solberg, Tore K., Gulati, Agnete M., Nygaard, Øystein P., Gulati, Sasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427907/
https://www.ncbi.nlm.nih.gov/pubmed/35852626
http://dx.doi.org/10.1007/s00701-022-05282-y
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author Johansen, Tonje Okkenhaug
Vangen-Lønne, Vetle
Holmberg, Siril T.
Salvesen, Øyvind O.
Solberg, Tore K.
Gulati, Agnete M.
Nygaard, Øystein P.
Gulati, Sasha
author_facet Johansen, Tonje Okkenhaug
Vangen-Lønne, Vetle
Holmberg, Siril T.
Salvesen, Øyvind O.
Solberg, Tore K.
Gulati, Agnete M.
Nygaard, Øystein P.
Gulati, Sasha
author_sort Johansen, Tonje Okkenhaug
collection PubMed
description BACKGROUND: The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year. METHODS: Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The primary outcome was change in the Neck Disability Index (NDI). Secondary outcomes were changes in the European Myelopathy Score (EMS), quality of life (EuroQoL EQ-5D), numeric rating scales (NRS) for headache, neck pain, and arm pain, and complications. RESULTS: Significant improvements in all patient-reported outcomes (PROMs) were detected for both age cohorts at 1 year. For the two age cohorts combined, there was a statistically significant improvement in the NDI score (mean 9.2, 95% CI 7.7 to 10.6, P < 0.001). There were no differences between age cohorts in mean change of NDI (− 8.9 vs. − 10.1, P = 0.48), EQ-5D (0.13 vs. 0.17, P = 0.37), or NRS pain scores, but elderly patients experienced a larger improvement in EMS (0.7 vs. 1.3, P = 0.02). A total of 74 patients (15.6%) in the younger cohort and 43 patients (24.3%) in the older cohort experienced complications or adverse effects within 3 months of surgery, mainly urinary and respiratory tract infections. CONCLUSION: Surgery for DCM was associated with significant improvement across a wide range of PROMs for both younger and elderly patients. Surgery for DCM should not be denied based on age alone.
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spelling pubmed-94279072022-09-01 Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes Johansen, Tonje Okkenhaug Vangen-Lønne, Vetle Holmberg, Siril T. Salvesen, Øyvind O. Solberg, Tore K. Gulati, Agnete M. Nygaard, Øystein P. Gulati, Sasha Acta Neurochir (Wien) Original Article - Spine degenerative BACKGROUND: The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year. METHODS: Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The primary outcome was change in the Neck Disability Index (NDI). Secondary outcomes were changes in the European Myelopathy Score (EMS), quality of life (EuroQoL EQ-5D), numeric rating scales (NRS) for headache, neck pain, and arm pain, and complications. RESULTS: Significant improvements in all patient-reported outcomes (PROMs) were detected for both age cohorts at 1 year. For the two age cohorts combined, there was a statistically significant improvement in the NDI score (mean 9.2, 95% CI 7.7 to 10.6, P < 0.001). There were no differences between age cohorts in mean change of NDI (− 8.9 vs. − 10.1, P = 0.48), EQ-5D (0.13 vs. 0.17, P = 0.37), or NRS pain scores, but elderly patients experienced a larger improvement in EMS (0.7 vs. 1.3, P = 0.02). A total of 74 patients (15.6%) in the younger cohort and 43 patients (24.3%) in the older cohort experienced complications or adverse effects within 3 months of surgery, mainly urinary and respiratory tract infections. CONCLUSION: Surgery for DCM was associated with significant improvement across a wide range of PROMs for both younger and elderly patients. Surgery for DCM should not be denied based on age alone. Springer Vienna 2022-07-19 2022 /pmc/articles/PMC9427907/ /pubmed/35852626 http://dx.doi.org/10.1007/s00701-022-05282-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article - Spine degenerative
Johansen, Tonje Okkenhaug
Vangen-Lønne, Vetle
Holmberg, Siril T.
Salvesen, Øyvind O.
Solberg, Tore K.
Gulati, Agnete M.
Nygaard, Øystein P.
Gulati, Sasha
Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
title Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
title_full Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
title_fullStr Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
title_full_unstemmed Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
title_short Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
title_sort surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
topic Original Article - Spine degenerative
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427907/
https://www.ncbi.nlm.nih.gov/pubmed/35852626
http://dx.doi.org/10.1007/s00701-022-05282-y
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