Cargando…
Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes
BACKGROUND: The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year. METHODS: Data were obtained from the Norwegian Registry for...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427907/ https://www.ncbi.nlm.nih.gov/pubmed/35852626 http://dx.doi.org/10.1007/s00701-022-05282-y |
_version_ | 1784778999585570816 |
---|---|
author | Johansen, Tonje Okkenhaug Vangen-Lønne, Vetle Holmberg, Siril T. Salvesen, Øyvind O. Solberg, Tore K. Gulati, Agnete M. Nygaard, Øystein P. Gulati, Sasha |
author_facet | Johansen, Tonje Okkenhaug Vangen-Lønne, Vetle Holmberg, Siril T. Salvesen, Øyvind O. Solberg, Tore K. Gulati, Agnete M. Nygaard, Øystein P. Gulati, Sasha |
author_sort | Johansen, Tonje Okkenhaug |
collection | PubMed |
description | BACKGROUND: The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year. METHODS: Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The primary outcome was change in the Neck Disability Index (NDI). Secondary outcomes were changes in the European Myelopathy Score (EMS), quality of life (EuroQoL EQ-5D), numeric rating scales (NRS) for headache, neck pain, and arm pain, and complications. RESULTS: Significant improvements in all patient-reported outcomes (PROMs) were detected for both age cohorts at 1 year. For the two age cohorts combined, there was a statistically significant improvement in the NDI score (mean 9.2, 95% CI 7.7 to 10.6, P < 0.001). There were no differences between age cohorts in mean change of NDI (− 8.9 vs. − 10.1, P = 0.48), EQ-5D (0.13 vs. 0.17, P = 0.37), or NRS pain scores, but elderly patients experienced a larger improvement in EMS (0.7 vs. 1.3, P = 0.02). A total of 74 patients (15.6%) in the younger cohort and 43 patients (24.3%) in the older cohort experienced complications or adverse effects within 3 months of surgery, mainly urinary and respiratory tract infections. CONCLUSION: Surgery for DCM was associated with significant improvement across a wide range of PROMs for both younger and elderly patients. Surgery for DCM should not be denied based on age alone. |
format | Online Article Text |
id | pubmed-9427907 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-94279072022-09-01 Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes Johansen, Tonje Okkenhaug Vangen-Lønne, Vetle Holmberg, Siril T. Salvesen, Øyvind O. Solberg, Tore K. Gulati, Agnete M. Nygaard, Øystein P. Gulati, Sasha Acta Neurochir (Wien) Original Article - Spine degenerative BACKGROUND: The aim of this study was to investigate whether clinical outcomes in patients aged ≥ 70 undergoing decompressive surgery for degenerative cervical myelopathy (DCM) differ from those of younger patients (50–70 years) at 1 year. METHODS: Data were obtained from the Norwegian Registry for Spine Surgery (NORspine). Among 651 patients included, 177 (27.2%) were ≥ 70 years old. The primary outcome was change in the Neck Disability Index (NDI). Secondary outcomes were changes in the European Myelopathy Score (EMS), quality of life (EuroQoL EQ-5D), numeric rating scales (NRS) for headache, neck pain, and arm pain, and complications. RESULTS: Significant improvements in all patient-reported outcomes (PROMs) were detected for both age cohorts at 1 year. For the two age cohorts combined, there was a statistically significant improvement in the NDI score (mean 9.2, 95% CI 7.7 to 10.6, P < 0.001). There were no differences between age cohorts in mean change of NDI (− 8.9 vs. − 10.1, P = 0.48), EQ-5D (0.13 vs. 0.17, P = 0.37), or NRS pain scores, but elderly patients experienced a larger improvement in EMS (0.7 vs. 1.3, P = 0.02). A total of 74 patients (15.6%) in the younger cohort and 43 patients (24.3%) in the older cohort experienced complications or adverse effects within 3 months of surgery, mainly urinary and respiratory tract infections. CONCLUSION: Surgery for DCM was associated with significant improvement across a wide range of PROMs for both younger and elderly patients. Surgery for DCM should not be denied based on age alone. Springer Vienna 2022-07-19 2022 /pmc/articles/PMC9427907/ /pubmed/35852626 http://dx.doi.org/10.1007/s00701-022-05282-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article - Spine degenerative Johansen, Tonje Okkenhaug Vangen-Lønne, Vetle Holmberg, Siril T. Salvesen, Øyvind O. Solberg, Tore K. Gulati, Agnete M. Nygaard, Øystein P. Gulati, Sasha Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
title | Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
title_full | Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
title_fullStr | Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
title_full_unstemmed | Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
title_short | Surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
title_sort | surgery for degenerative cervical myelopathy in the elderly: a nationwide registry-based observational study with patient-reported outcomes |
topic | Original Article - Spine degenerative |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427907/ https://www.ncbi.nlm.nih.gov/pubmed/35852626 http://dx.doi.org/10.1007/s00701-022-05282-y |
work_keys_str_mv | AT johansentonjeokkenhaug surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT vangenlønnevetle surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT holmbergsirilt surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT salvesenøyvindo surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT solbergtorek surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT gulatiagnetem surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT nygaardøysteinp surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes AT gulatisasha surgeryfordegenerativecervicalmyelopathyintheelderlyanationwideregistrybasedobservationalstudywithpatientreportedoutcomes |