Clinical parameter-based prediction of DNA methylation classification generates a prediction model of prognosis in patients with juvenile myelomonocytic leukemia

Juvenile myelomonocytic leukemia (JMML) is a rare heterogeneous hematological malignancy of early childhood characterized by causative RAS pathway mutations. Classifying patients with JMML using global DNA methylation profiles is useful for risk stratification. We implemented machine learning algori...

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Detalles Bibliográficos
Autores principales: Imaizumi, Takahiro, Meyer, Julia, Wakamatsu, Manabu, Kitazawa, Hironobu, Murakami, Norihiro, Okuno, Yusuke, Yoshida, Taro, Sajiki, Daichi, Hama, Asahito, Kojima, Seiji, Takahashi, Yoshiyuki, Loh, Mignon, Stieglitz, Elliot, Muramatsu, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427938/
https://www.ncbi.nlm.nih.gov/pubmed/36042365
http://dx.doi.org/10.1038/s41598-022-18733-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427938/
https://www.ncbi.nlm.nih.gov/pubmed/36042365
http://dx.doi.org/10.1038/s41598-022-18733-4

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