Decreased NHE3 expression in colon cancer is associated with DNA damage, increased inflammation and tumor growth

Dysregulation of intra- and extracellular pH in cancer contributes to extracellular matrix remodeling, favors cell migration, proliferation, and metastasis. Although the primary attention has been focused on the role of the ubiquitous Na(+)/H(+) exchanger isoform NHE1, the role of NHE3, the predomin...

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Detalles Bibliográficos
Autores principales: Laubitz, Daniel, Gurney, Michael A., Midura-Kiela, Monica, Clutter, Christy, Besselsen, David G., Chen, Hao, Ghishan, Fayez K., Kiela, Pawel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427942/
https://www.ncbi.nlm.nih.gov/pubmed/36042372
http://dx.doi.org/10.1038/s41598-022-19091-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427942/
https://www.ncbi.nlm.nih.gov/pubmed/36042372
http://dx.doi.org/10.1038/s41598-022-19091-x

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