Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder

Mitochondrial dysfunction is a neurobiological phenomenon implicated in the pathophysiology of schizophrenia and bipolar disorder that can synergistically affect synaptic neurotransmission. We hypothesized that schizophrenia and bipolar disorder share molecular alterations at the mitochondrial and s...

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Detalles Bibliográficos
Autores principales: Das, Sujan C., Hjelm, Brooke E., Rollins, Brandi L., Sequeira, Adolfo, Morgan, Ling, Omidsalar, Audrey A., Schatzberg, Alan F., Barchas, Jack D., Lee, Francis S., Myers, Richard M., Watson, Stanley J., Akil, Huda, Bunney, William E., Vawter, Marquis P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427957/
https://www.ncbi.nlm.nih.gov/pubmed/36042222
http://dx.doi.org/10.1038/s41398-022-02127-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427957/
https://www.ncbi.nlm.nih.gov/pubmed/36042222
http://dx.doi.org/10.1038/s41398-022-02127-1

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