Porcine deltacoronavirus E protein induces interleukin-8 production via NF-κB and AP-1 activation

Infection induces the production of proinflammatory cytokines and chemokines such as interleukin-8 (IL-8) and interleukin-6 (IL-6). Although they facilitate local antiviral immunity, their excessive release leads to life-threatening cytokine release syndrome, exemplified by the severe cases of coron...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Shi, Zhaorong, Chen, Jianfei, Zhang, Hongling, Li, Mingwei, Zhao, Ying, Shi, Hongyan, Shi, Da, Guo, Longjun, Feng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428115/
https://www.ncbi.nlm.nih.gov/pubmed/36181744
http://dx.doi.org/10.1016/j.vetmic.2022.109553

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