Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy

Intestinal barrier derangement allows intestinal bacteria and their products to translocate to the systemic circulation. Pseudomonas aeruginosa (PA) superimposed infection in critically ill patients increases gut permeability and leads to gut-driven sepsis. PA infections are challenging due to multi...

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Detalles Bibliográficos
Autores principales: Singh, Vijay K., Almpani, Marianna, Maura, Damien, Kitao, Tomoe, Ferrari, Livia, Fontana, Stefano, Bergamini, Gabriella, Calcaterra, Elisa, Pignaffo, Chiara, Negri, Michele, de Oliveira Pereira, Thays, Skinner, Frances, Gkikas, Manos, Andreotti, Danielle, Felici, Antonio, Déziel, Eric, Lépine, Francois, Rahme, Laurence G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428149/
https://www.ncbi.nlm.nih.gov/pubmed/36042245
http://dx.doi.org/10.1038/s41467-022-32833-9

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