Inhibitory effect of the novel tyrosine kinase inhibitor DCC-2036 on triple-negative breast cancer stem cells through AXL-KLF5 positive feedback loop

Triple-negative breast cancer (TNBC), an aggressive histological subtype of breast cancer, exhibits a high risk of early recurrence rate and a poor prognosis, and it is primarily associated with the abundance of cancer stem cells (CSCs). At present, the strategies for effectively eradicating or inhi...

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Detalles Bibliográficos
Autores principales: Shen, Yingying, Zhu, Qingyun, Xiao, Maoyu, Yin, Liyang, Feng, Wenjie, Feng, Jianbo, He, Jun, Li, Pei, Chen, Xiguang, Ding, Wenjun, Zhong, Jing, Zeng, Zhaolin, Xie, Zhuoye, Liu, Jianghua, Zu, Xuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428169/
https://www.ncbi.nlm.nih.gov/pubmed/36042208
http://dx.doi.org/10.1038/s41419-022-05185-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428169/
https://www.ncbi.nlm.nih.gov/pubmed/36042208
http://dx.doi.org/10.1038/s41419-022-05185-x

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