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Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST

SETTING: Treatment of tuberculosis (TB) can result in Drug-Induced Liver Injury (DILI) since hepatotoxic metabolites are formed during the biotransformation of isoniazid (INH). DILI can be related to the genetic profile of the patient. Single nucleotide polymorphisms in the CYP2E1 gene and GSTM1 and...

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Detalles Bibliográficos
Autores principales:	Santos, Eliana Abreu, Gonçalves, José Carlos Saraiva, Fleury, Marcos K., Kritski, Afrânio L., Oliveira, Martha M., Velasque, Luciane S., e Silva, José Roberto Lapa, Estrela, Rita de Cássia E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428211/ https://www.ncbi.nlm.nih.gov/pubmed/31697922 http://dx.doi.org/10.1016/j.bjid.2019.09.003

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