In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo

In vitro differentiation of human induced pluripotent stem cells (iPSCs) into beta cells represents an important cell source for diabetes research. Here, we fully characterized iPSC-derived beta cell function in vitro and in vivo in humanized mice. Using a 7-stage protocol, human iPSCs were differen...

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Detalles Bibliográficos
Autores principales: Fantuzzi, Federica, Toivonen, Sanna, Schiavo, Andrea Alex, Chae, Heeyoung, Tariq, Mohammad, Sawatani, Toshiaki, Pachera, Nathalie, Cai, Ying, Vinci, Chiara, Virgilio, Enrico, Ladriere, Laurence, Suleiman, Mara, Marchetti, Piero, Jonas, Jean-Christophe, Gilon, Patrick, Eizirik, Décio L., Igoillo-Esteve, Mariana, Cnop, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428245/
https://www.ncbi.nlm.nih.gov/pubmed/36060810
http://dx.doi.org/10.3389/fcell.2022.967765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428245/
https://www.ncbi.nlm.nih.gov/pubmed/36060810
http://dx.doi.org/10.3389/fcell.2022.967765

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