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Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review

BACKGROUND: Flow diverters (FDs) for the treatment of basilar artery (BA) aneurysms remain controversial. In this study, we report our initial experience of flow diversion for treatment of this pathology. METHODS: Consecutive patients with an aneurysm of the BA that was treated by implantation of th...

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Autores principales: Wang, Chuanchuan, Zhu, Deyuan, Xu, Xiaolong, Zhou, Yu, Zhao, Rui, Li, Qiang, Yang, Pengfei, Huang, Qinghai, Xu, Yi, Liu, Jianmin, Fang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428249/
https://www.ncbi.nlm.nih.gov/pubmed/36062016
http://dx.doi.org/10.3389/fneur.2022.990308
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author Wang, Chuanchuan
Zhu, Deyuan
Xu, Xiaolong
Zhou, Yu
Zhao, Rui
Li, Qiang
Yang, Pengfei
Huang, Qinghai
Xu, Yi
Liu, Jianmin
Fang, Yibin
author_facet Wang, Chuanchuan
Zhu, Deyuan
Xu, Xiaolong
Zhou, Yu
Zhao, Rui
Li, Qiang
Yang, Pengfei
Huang, Qinghai
Xu, Yi
Liu, Jianmin
Fang, Yibin
author_sort Wang, Chuanchuan
collection PubMed
description BACKGROUND: Flow diverters (FDs) for the treatment of basilar artery (BA) aneurysms remain controversial. In this study, we report our initial experience of flow diversion for treatment of this pathology. METHODS: Consecutive patients with an aneurysm of the BA that was treated by implantation of the FD were included in our retrospective study. Procedural complications, aneurysm occlusion, and a functional outcome were evaluated. FD placement in BA for aneurysm treatment reported in the literature was also reviewed and summarized. RESULTS: Sixteen patients with 16 BA aneurysms were treated by FD implantation with (n = 8) or without (n = 8) adjunctive coiling. The Tubridge was used in 13 (81.3%) and Pipeline in 3 (18.8%) procedures. Average aneurysm size was 15.7 mm. Four aneurysms were located at the basilar apex, six at the basilar trunk, and six at the vertebrobasilar junction. Three patients experienced procedural complications (18.8%), including two ischemic strokes and one hydrocephalus, with resultant mortality in one case (6.3%). Median follow-up was 7.7 months and available for 15 aneurysms. Complete/near-complete occlusion was seen in 13 (86.7%) aneurysms. CONCLUSION: In our initial experience, flow diversion is feasible and safe in the treatment of BA aneurysms with promising occlusion rates at mid-term follow-up. Larger cohort studies are required to validate these results.
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spelling pubmed-94282492022-09-01 Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review Wang, Chuanchuan Zhu, Deyuan Xu, Xiaolong Zhou, Yu Zhao, Rui Li, Qiang Yang, Pengfei Huang, Qinghai Xu, Yi Liu, Jianmin Fang, Yibin Front Neurol Neurology BACKGROUND: Flow diverters (FDs) for the treatment of basilar artery (BA) aneurysms remain controversial. In this study, we report our initial experience of flow diversion for treatment of this pathology. METHODS: Consecutive patients with an aneurysm of the BA that was treated by implantation of the FD were included in our retrospective study. Procedural complications, aneurysm occlusion, and a functional outcome were evaluated. FD placement in BA for aneurysm treatment reported in the literature was also reviewed and summarized. RESULTS: Sixteen patients with 16 BA aneurysms were treated by FD implantation with (n = 8) or without (n = 8) adjunctive coiling. The Tubridge was used in 13 (81.3%) and Pipeline in 3 (18.8%) procedures. Average aneurysm size was 15.7 mm. Four aneurysms were located at the basilar apex, six at the basilar trunk, and six at the vertebrobasilar junction. Three patients experienced procedural complications (18.8%), including two ischemic strokes and one hydrocephalus, with resultant mortality in one case (6.3%). Median follow-up was 7.7 months and available for 15 aneurysms. Complete/near-complete occlusion was seen in 13 (86.7%) aneurysms. CONCLUSION: In our initial experience, flow diversion is feasible and safe in the treatment of BA aneurysms with promising occlusion rates at mid-term follow-up. Larger cohort studies are required to validate these results. Frontiers Media S.A. 2022-08-17 /pmc/articles/PMC9428249/ /pubmed/36062016 http://dx.doi.org/10.3389/fneur.2022.990308 Text en Copyright © 2022 Wang, Zhu, Xu, Zhou, Zhao, Li, Yang, Huang, Xu, Liu and Fang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Wang, Chuanchuan
Zhu, Deyuan
Xu, Xiaolong
Zhou, Yu
Zhao, Rui
Li, Qiang
Yang, Pengfei
Huang, Qinghai
Xu, Yi
Liu, Jianmin
Fang, Yibin
Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review
title Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review
title_full Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review
title_fullStr Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review
title_full_unstemmed Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review
title_short Use of flow diverter device in basilar artery for aneurysm treatment: Case series and literature review
title_sort use of flow diverter device in basilar artery for aneurysm treatment: case series and literature review
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428249/
https://www.ncbi.nlm.nih.gov/pubmed/36062016
http://dx.doi.org/10.3389/fneur.2022.990308
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