Developing high-affinity decoy receptors to treat multiple myeloma and diffuse large B cell lymphoma

Disease relapse and treatment-induced immunotoxicity pose significant clinical challenges for patients with hematological cancers. Here, we reveal distinctive requirements for neutralizing TNF receptor ligands APRIL and BAFF and their receptor activity in MM and DLBCL, impacting protein translation...

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Detalles Bibliográficos
Autores principales: Miao, Yu Rebecca, Thakkar, Kaushik, Cenik, Can, Jiang, Dadi, Mizuno, Kazue, Jia, Chenjun, Li, Caiyun Grace, Zhao, Hongjuan, Diep, Anh, Xu, Yu, Zhang, Xin Eric, Yang, Teddy Tat Chi, Liedtke, Michaela, Abidi, Parveen, Leung, Wing-sze, Koong, Albert C., Giaccia, Amato J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428257/
https://www.ncbi.nlm.nih.gov/pubmed/35881112
http://dx.doi.org/10.1084/jem.20220214

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