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Rotational intraperitoneal pressurized aerosol chemotherapy with paclitaxel and cisplatin: pharmacokinetics, tissue concentrations, and toxicities in a pig model

OBJECTIVE: We used paclitaxel and cisplatin, known to be effective in intraperitoneal chemotherapy, in a novel prototype of rotational intraperitoneal pressurized aerosol chemotherapy (RIPAC) and evaluated the pharmacokinetics, tissue concentrations, and toxicities in a pig model. METHODS: We develo...

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Detalles Bibliográficos
Autores principales: Park, Soo Jin, Lee, Eun Ji, Seol, Aeran, Park, Sunwoo, Ham, Jiyeon, Yim, Ga Won, Shim, Seung-Hyuk, Lim, Whasun, Chang, Suk-Joon, Song, Gwonhwa, Park, Ji Won, Kim, Hee Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian Society of Gynecologic Oncology; Korean Society of Gynecologic Oncology; Japan Society of Gynecologic Oncology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428304/
https://www.ncbi.nlm.nih.gov/pubmed/35712969
http://dx.doi.org/10.3802/jgo.2022.33.e56