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A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention

BACKGROUND AND AIMS: Early detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000. This study aimed to establish a nomogram predicting 30-day mortality after PCI. MATERIALS AND METHODS:...

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Autores principales: Song, Jingjing, Liu, Yupeng, Wang, Wenyao, Chen, Jing, Yang, Jie, Wen, Jun, Gao, Jun, Shao, Chunli, Tang, Yi-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428350/
https://www.ncbi.nlm.nih.gov/pubmed/36061568
http://dx.doi.org/10.3389/fcvm.2022.897020
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author Song, Jingjing
Liu, Yupeng
Wang, Wenyao
Chen, Jing
Yang, Jie
Wen, Jun
Gao, Jun
Shao, Chunli
Tang, Yi-Da
author_facet Song, Jingjing
Liu, Yupeng
Wang, Wenyao
Chen, Jing
Yang, Jie
Wen, Jun
Gao, Jun
Shao, Chunli
Tang, Yi-Da
author_sort Song, Jingjing
collection PubMed
description BACKGROUND AND AIMS: Early detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000. This study aimed to establish a nomogram predicting 30-day mortality after PCI. MATERIALS AND METHODS: In total, 10,444 patients undergoing PCI in National Center for Cardiovascular Diseases in China were enrolled to establish a nomogram to predict 30-day mortality after PCI. The nomogram was generated by incorporating parameters selected by logistic regression with the stepwise backward method. RESULTS: Five features were selected to build the nomogram, including age, male sex, cardiac dysfunction, STEMI, and TIMI 0–2 after PCI. The performance of the nomogram was evaluated, and the area under the curves (AUC) was 0.881 (95% CI: 0.8–0.961). Our nomogram exhibited better performance than a previous risk model (AUC = 0.7, 95% CI: 0.586–0.813) established by Brener et al. The survival curve successfully stratified the patients above and below the median score of 4. CONCLUSION: A novel nomogram for predicting 30-day mortality was established in unselected patients undergoing PCI, which may help risk stratification in clinical practice.
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spelling pubmed-94283502022-09-01 A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention Song, Jingjing Liu, Yupeng Wang, Wenyao Chen, Jing Yang, Jie Wen, Jun Gao, Jun Shao, Chunli Tang, Yi-Da Front Cardiovasc Med Cardiovascular Medicine BACKGROUND AND AIMS: Early detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000. This study aimed to establish a nomogram predicting 30-day mortality after PCI. MATERIALS AND METHODS: In total, 10,444 patients undergoing PCI in National Center for Cardiovascular Diseases in China were enrolled to establish a nomogram to predict 30-day mortality after PCI. The nomogram was generated by incorporating parameters selected by logistic regression with the stepwise backward method. RESULTS: Five features were selected to build the nomogram, including age, male sex, cardiac dysfunction, STEMI, and TIMI 0–2 after PCI. The performance of the nomogram was evaluated, and the area under the curves (AUC) was 0.881 (95% CI: 0.8–0.961). Our nomogram exhibited better performance than a previous risk model (AUC = 0.7, 95% CI: 0.586–0.813) established by Brener et al. The survival curve successfully stratified the patients above and below the median score of 4. CONCLUSION: A novel nomogram for predicting 30-day mortality was established in unselected patients undergoing PCI, which may help risk stratification in clinical practice. Frontiers Media S.A. 2022-08-17 /pmc/articles/PMC9428350/ /pubmed/36061568 http://dx.doi.org/10.3389/fcvm.2022.897020 Text en Copyright © 2022 Song, Liu, Wang, Chen, Yang, Wen, Gao, Shao and Tang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Song, Jingjing
Liu, Yupeng
Wang, Wenyao
Chen, Jing
Yang, Jie
Wen, Jun
Gao, Jun
Shao, Chunli
Tang, Yi-Da
A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
title A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
title_full A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
title_fullStr A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
title_full_unstemmed A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
title_short A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
title_sort nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428350/
https://www.ncbi.nlm.nih.gov/pubmed/36061568
http://dx.doi.org/10.3389/fcvm.2022.897020
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