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A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention
BACKGROUND AND AIMS: Early detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000. This study aimed to establish a nomogram predicting 30-day mortality after PCI. MATERIALS AND METHODS:...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428350/ https://www.ncbi.nlm.nih.gov/pubmed/36061568 http://dx.doi.org/10.3389/fcvm.2022.897020 |
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author | Song, Jingjing Liu, Yupeng Wang, Wenyao Chen, Jing Yang, Jie Wen, Jun Gao, Jun Shao, Chunli Tang, Yi-Da |
author_facet | Song, Jingjing Liu, Yupeng Wang, Wenyao Chen, Jing Yang, Jie Wen, Jun Gao, Jun Shao, Chunli Tang, Yi-Da |
author_sort | Song, Jingjing |
collection | PubMed |
description | BACKGROUND AND AIMS: Early detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000. This study aimed to establish a nomogram predicting 30-day mortality after PCI. MATERIALS AND METHODS: In total, 10,444 patients undergoing PCI in National Center for Cardiovascular Diseases in China were enrolled to establish a nomogram to predict 30-day mortality after PCI. The nomogram was generated by incorporating parameters selected by logistic regression with the stepwise backward method. RESULTS: Five features were selected to build the nomogram, including age, male sex, cardiac dysfunction, STEMI, and TIMI 0–2 after PCI. The performance of the nomogram was evaluated, and the area under the curves (AUC) was 0.881 (95% CI: 0.8–0.961). Our nomogram exhibited better performance than a previous risk model (AUC = 0.7, 95% CI: 0.586–0.813) established by Brener et al. The survival curve successfully stratified the patients above and below the median score of 4. CONCLUSION: A novel nomogram for predicting 30-day mortality was established in unselected patients undergoing PCI, which may help risk stratification in clinical practice. |
format | Online Article Text |
id | pubmed-9428350 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94283502022-09-01 A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention Song, Jingjing Liu, Yupeng Wang, Wenyao Chen, Jing Yang, Jie Wen, Jun Gao, Jun Shao, Chunli Tang, Yi-Da Front Cardiovasc Med Cardiovascular Medicine BACKGROUND AND AIMS: Early detection of mortality after percutaneous coronary intervention (PCI) is crucial, whereas most risk prediction models are based on outdated cohorts before the year 2000. This study aimed to establish a nomogram predicting 30-day mortality after PCI. MATERIALS AND METHODS: In total, 10,444 patients undergoing PCI in National Center for Cardiovascular Diseases in China were enrolled to establish a nomogram to predict 30-day mortality after PCI. The nomogram was generated by incorporating parameters selected by logistic regression with the stepwise backward method. RESULTS: Five features were selected to build the nomogram, including age, male sex, cardiac dysfunction, STEMI, and TIMI 0–2 after PCI. The performance of the nomogram was evaluated, and the area under the curves (AUC) was 0.881 (95% CI: 0.8–0.961). Our nomogram exhibited better performance than a previous risk model (AUC = 0.7, 95% CI: 0.586–0.813) established by Brener et al. The survival curve successfully stratified the patients above and below the median score of 4. CONCLUSION: A novel nomogram for predicting 30-day mortality was established in unselected patients undergoing PCI, which may help risk stratification in clinical practice. Frontiers Media S.A. 2022-08-17 /pmc/articles/PMC9428350/ /pubmed/36061568 http://dx.doi.org/10.3389/fcvm.2022.897020 Text en Copyright © 2022 Song, Liu, Wang, Chen, Yang, Wen, Gao, Shao and Tang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Song, Jingjing Liu, Yupeng Wang, Wenyao Chen, Jing Yang, Jie Wen, Jun Gao, Jun Shao, Chunli Tang, Yi-Da A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
title | A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
title_full | A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
title_fullStr | A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
title_full_unstemmed | A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
title_short | A nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
title_sort | nomogram predicting 30-day mortality in patients undergoing percutaneous coronary intervention |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428350/ https://www.ncbi.nlm.nih.gov/pubmed/36061568 http://dx.doi.org/10.3389/fcvm.2022.897020 |
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