Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?

There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of them are in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cells through the renin-angiotensin system (RAS) via the angiotensin-converting...

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Autores principales: Barekat, Maryam, Shahrbaf, Mohammad Amin, Rahi, Kosar, Vosough, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2022
Materias:
Letter to The Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428472/
https://www.ncbi.nlm.nih.gov/pubmed/36043411
http://dx.doi.org/10.22074/cellj.2022.8487
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author Barekat, Maryam
Shahrbaf, Mohammad Amin
Rahi, Kosar
Vosough, Massoud
author_facet Barekat, Maryam
Shahrbaf, Mohammad Amin
Rahi, Kosar
Vosough, Massoud
author_sort Barekat, Maryam
collection PubMed
description There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of them are in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cells through the renin-angiotensin system (RAS) via the angiotensin-converting enzyme 2 (ACE2) receptor. RAS activation is associated with pro-inflammatory effects through the ACE/Ang II/ Angiotensin II type 1 receptor (AT1R) pathway or anti-inflammatory effects through ACE2/Ang1-7/Mas axis. In the current paper, we discuss the pathophysiology of newly diagnosed HTN and its effect on morbidity in patients with coronavirus disease 2019 (COVID-19).
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spelling pubmed-94284722022-09-03 Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence? Barekat, Maryam Shahrbaf, Mohammad Amin Rahi, Kosar Vosough, Massoud Cell J Letter to The Editor There are a lot of data about the correlation of SARS-CoV-2 infection and hypertension (HTN), but most of them are in the increased risk of morbidity and mortality in patients with HTN. SARS-CoV-2 can interfere with host cells through the renin-angiotensin system (RAS) via the angiotensin-converting enzyme 2 (ACE2) receptor. RAS activation is associated with pro-inflammatory effects through the ACE/Ang II/ Angiotensin II type 1 receptor (AT1R) pathway or anti-inflammatory effects through ACE2/Ang1-7/Mas axis. In the current paper, we discuss the pathophysiology of newly diagnosed HTN and its effect on morbidity in patients with coronavirus disease 2019 (COVID-19). Royan Institute 2022-07 2022-07-27 /pmc/articles/PMC9428472/ /pubmed/36043411 http://dx.doi.org/10.22074/cellj.2022.8487 Text en Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited. https://creativecommons.org/licenses/by-nc/3.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial 3.0 (CC BY-NC 3.0) License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to The Editor
Barekat, Maryam
Shahrbaf, Mohammad Amin
Rahi, Kosar
Vosough, Massoud
Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
title Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
title_full Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
title_fullStr Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
title_full_unstemmed Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
title_short Hypertension in COVID-19, A Risk Factor for Infection or A Late Consequence?
title_sort hypertension in covid-19, a risk factor for infection or a late consequence?
topic Letter to The Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428472/
https://www.ncbi.nlm.nih.gov/pubmed/36043411
http://dx.doi.org/10.22074/cellj.2022.8487
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AT shahrbafmohammadamin hypertensionincovid19ariskfactorforinfectionoralateconsequence
AT rahikosar hypertensionincovid19ariskfactorforinfectionoralateconsequence
AT vosoughmassoud hypertensionincovid19ariskfactorforinfectionoralateconsequence

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