Associations between polygenic risk of coronary artery disease and type 2 diabetes, lifestyle, and cardiovascular mortality: A prospective UK Biobank study

BACKGROUND: Previous studies primarily targeted the ability of polygenic risk scores (PRSs) to predict a specific disease, and only a few studies have investigated the association between genetic risk scores and cardiovascular (CV) mortality. We assessed PRSs for coronary artery disease (CAD) and ty...

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Autores principales: Yun, Jae-Seung, Jung, Sang-Hyuk, Shivakumar, Manu, Xiao, Brenda, Khera, Amit V., Park, Woong-Yang, Won, Hong-Hee, Kim, Dokyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428483/
https://www.ncbi.nlm.nih.gov/pubmed/36061534
http://dx.doi.org/10.3389/fcvm.2022.919374

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