Cargando…
Mechanisms of carcinogenic activity triggered by lysine-specific demethylase 1A
Epigenetics has emerged as a prime focus area in the field of cancer research. Lysine-specific demethylase 1A (LSD1), the first discovered histone demethylase, is mainly responsible for catalysing demethylation of histone 3 lysine 4 (H3K4) and H3K9 to activate or inhibit gene transcription. LSD1 is...
Autores principales: | Yang, Chao, Li, Dan, Zang, Shaohong, Zhang, Lei, Zhong, Zhangfeng, Zhou, Yingtang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428822/ https://www.ncbi.nlm.nih.gov/pubmed/36059955 http://dx.doi.org/10.3389/fphar.2022.955218 |
Ejemplares similares
-
Nanocarriers for effective delivery: modulation of innate immunity for the management of infections and the associated complications
por: Ko, Chung-Nga, et al.
Publicado: (2022) -
Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1
por: Zhou, Chao, et al.
Publicado: (2017) -
Functional Characterization of the Lysine-Specific Histone Demethylases Family in Soybean
por: Liu, Mengshi, et al.
Publicado: (2022) -
Chemical Biology of Lysine Demethylases
por: Heightman, Tom D
Publicado: (2011) -
Discovery of orally active chalcones as histone lysine specific demethylase 1 inhibitors for the treatment of leukaemia
por: Li, Yang, et al.
Publicado: (2020)