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Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults

Several step‐based daily targets have been widely circulated, but there is a lack of empirical population‐based evidence to support such guidance. We examined dose‐response associations between step count and classical CVD risk markers (glycated hemoglobin, high density lipoprotein cholesterol, trig...

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Autores principales: Hamer, Mark, Blodgett, Joanna M., Stamatakis, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428935/
https://www.ncbi.nlm.nih.gov/pubmed/35460292
http://dx.doi.org/10.1111/sms.14173
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author Hamer, Mark
Blodgett, Joanna M.
Stamatakis, Emmanuel
author_facet Hamer, Mark
Blodgett, Joanna M.
Stamatakis, Emmanuel
author_sort Hamer, Mark
collection PubMed
description Several step‐based daily targets have been widely circulated, but there is a lack of empirical population‐based evidence to support such guidance. We examined dose‐response associations between step count and classical CVD risk markers (glycated hemoglobin, high density lipoprotein cholesterol, triglycerides, and C‐reactive protein) in 4665 adults (aged 46 years; 51.4% female) in a cross‐sectional study. Step counts were measured from a thigh mounted accelerometer (activPAL) worn over 7 days. The shape of the dose‐response curve for most risk markers was “L‐shaped,” with linear risk reduction up to around 10 000 steps a day. Controlling for stepping intensity did not materially alter our results.
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spelling pubmed-94289352022-09-08 Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults Hamer, Mark Blodgett, Joanna M. Stamatakis, Emmanuel Scand J Med Sci Sports Brief Report Several step‐based daily targets have been widely circulated, but there is a lack of empirical population‐based evidence to support such guidance. We examined dose‐response associations between step count and classical CVD risk markers (glycated hemoglobin, high density lipoprotein cholesterol, triglycerides, and C‐reactive protein) in 4665 adults (aged 46 years; 51.4% female) in a cross‐sectional study. Step counts were measured from a thigh mounted accelerometer (activPAL) worn over 7 days. The shape of the dose‐response curve for most risk markers was “L‐shaped,” with linear risk reduction up to around 10 000 steps a day. Controlling for stepping intensity did not materially alter our results. John Wiley and Sons Inc. 2022-04-28 2022-07 /pmc/articles/PMC9428935/ /pubmed/35460292 http://dx.doi.org/10.1111/sms.14173 Text en © 2022 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Hamer, Mark
Blodgett, Joanna M.
Stamatakis, Emmanuel
Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
title Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
title_full Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
title_fullStr Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
title_full_unstemmed Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
title_short Dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
title_sort dose‐response association between step count and cardiovascular disease risk markers in middle‐aged adults
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428935/
https://www.ncbi.nlm.nih.gov/pubmed/35460292
http://dx.doi.org/10.1111/sms.14173
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AT stamatakisemmanuel doseresponseassociationbetweenstepcountandcardiovasculardiseaseriskmarkersinmiddleagedadults