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The introduction of an N-glycosylation site into prochymosin greatly enhances its production and secretion by Pichia pastoris
BACKGROUND: N-glycosylation is one of the most important post-translational modifications. Many studies have shown that N-glycosylation has a significant effect on the secretion level of heterologous glycoproteins in yeast cells. However, there have been few studies reporting a clear and unified exp...
Autores principales: | Wang, Nan, Yang, Caifeng, Peng, Huakang, Guo, Wenfang, Wang, Mengqi, Li, Gangqiang, Liu, Dehu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429577/ https://www.ncbi.nlm.nih.gov/pubmed/36042512 http://dx.doi.org/10.1186/s12934-022-01904-3 |
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