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Dynamically modeling the effective range of IL-2 dosage in the treatment of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease characterized by an overactive immune response to self-antigen. The overactivation of CD4(+) Foxp3(−) conventional T cells (Tcons) and the inactivation of CD4(+) CD25(+) Foxp3(+) regulatory T cells (Tregs) play important rol...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429801/ https://www.ncbi.nlm.nih.gov/pubmed/36060072 http://dx.doi.org/10.1016/j.isci.2022.104911 |