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Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is Not Altered in Response to Specific Silencing

African trypanosomes evade the immune system of the mammalian host by the antigenic variation of the predominant glycosylphosphatidylinositol (GPI)-anchored surface protein, variant surface glycoprotein (VSG). VSG is a very stable protein that is turned over from the cell surface with a long half-li...

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Detalles Bibliográficos
Autores principales: Sharif, Mohamed, Garrison, Paige, Bush, Peter, Bangs, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429888/
https://www.ncbi.nlm.nih.gov/pubmed/35727016
http://dx.doi.org/10.1128/msphere.00122-22