Angiotensin-Converting Enzyme 2 Potentiates SARS-CoV-2 Infection by Antagonizing Type I Interferon Induction and Its Down-Stream Signaling Pathway

The innate interferon (IFN) response constitutes the first line of host defense against viral infections. It has been shown that IFN-I/III treatment could effectively contain severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro. However, how SARS-CoV-2 survives through t...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Liu, Jian, Chen, Zhilu, Peng, Haoran, Zhu, Cuisong, Feng, Daobin, Zhang, Shuye, Zhao, Ping, Zhang, Xiaoyan, Xu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429913/
https://www.ncbi.nlm.nih.gov/pubmed/35862802
http://dx.doi.org/10.1128/msphere.00211-22

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