RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge

The ongoing COVID-19 pandemic has contributed largely to the global vaccine disparity. Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines delivered to low-income countries. Here, we evaluated the efficacy of a three-dose virus-like particle (VLP) vaccine compos...

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Detalles Bibliográficos
Autores principales: Wong, Ting Y., Russ, Brynnan P., Lee, Katherine S., Miller, Olivia A., Kang, Jason, Cooper, Melissa, Winters, Michael T., Rodriguez-Aponte, Sergio A., Dalvie, Neil C., Johnston, Ryan S., Rader, Nathaniel A., Wong, Zeriel Y., Cyphert, Holly A., Martinez, Ivan, Shaligram, Umesh, Batwal, Saurabh, Lothe, Rakesh, Chandrasekaran, Rahul, Nagar, Gaurav, Rajurkar, Meghraj, Rao, Harish, Bevere, Justin R., Barbier, Mariette, Love, J. Christopher, Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429941/
https://www.ncbi.nlm.nih.gov/pubmed/35968964
http://dx.doi.org/10.1128/msphere.00243-22

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