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Human ACE2 Genetic Polymorphism Affecting SARS-CoV and SARS-CoV-2 Entry into Cells

Severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 have a single envelope glycoprotein (S protein) that binds to human angiotensin-converting enzyme 2 (ACE2) on the host cell membrane. Previous mutational scanning studies have suggested that some substitutions corresponding to s...

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Detalles Bibliográficos
Autores principales: Hattori, Takanari, Saito, Takeshi, Okuya, Kosuke, Takahashi, Yuji, Miyamoto, Hiroko, Kajihara, Masahiro, Igarashi, Manabu, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430119/
https://www.ncbi.nlm.nih.gov/pubmed/35862965
http://dx.doi.org/10.1128/spectrum.00870-22

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