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Prediction of Th1 and Cytotoxic T Lymphocyte Epitopes of Mycobacterium tuberculosis and Evaluation of Their Potential in the Diagnosis of Tuberculosis in a Mouse Model and in Humans

Latent tuberculosis infection (LTBI) is the primary source of tuberculosis (TB) but there is no suitable detection method to distinguish LTBI from active tuberculosis (ATB). In this study, five antigens of Mycobacterium tuberculosis belonging to LTBI and regions of difference (RDs) were selected to...

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Detalles Bibliográficos
Autores principales: Gong, Wenping, Liang, Yan, Wang, Jie, Liu, Yinping, Xue, Yong, Mi, Jie, Li, Pengchuan, Wang, Xiaoou, Wang, Lan, Wu, Xueqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430503/
https://www.ncbi.nlm.nih.gov/pubmed/35938824
http://dx.doi.org/10.1128/spectrum.01438-22