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Evaluation of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase (DAHPS) as a Vulnerable Target in Mycobacterium tuberculosis

Tuberculosis (TB) remains one of the leading causes of death due to a single pathogen. The emergence and proliferation of multidrug-resistant (MDR-TB) and extensively drug-resistant strains (XDR-TB) represent compelling reasons to invest in the pursuit of new anti-TB agents. The shikimate pathway, r...

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Detalles Bibliográficos
Autores principales: Galina, Luiza, Hopf, Fernanda S. M., Abbadi, Bruno Lopes, Sperotto, Nathalia D. de Moura, Czeczot, Alexia M., Duque-Villegas, Mario A., Perello, Marcia Alberton, Matter, Letícia Beatriz, de Souza, Eduardo Vieira, Parish, Tanya, Machado, Pablo, Basso, Luiz A., Bizarro, Cristiano V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430761/
https://www.ncbi.nlm.nih.gov/pubmed/35862980
http://dx.doi.org/10.1128/spectrum.00728-22

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