Increased Expression and Amplification of bla(KPC-2) Contributes to Resistance to Ceftazidime/Avibactam in a Sequence Type 11 Carbapenem-Resistant Klebsiella pneumoniae Strain

Ceftazidime/avibactam (CAZ/AVI) is regarded as an effective alternative antibiotic for the clinical treatment of Klebsiella pneumoniae carbapenemase (KPC)-producing isolates. As resistance has been reported in some strains, it is critical to understand the key mechanisms contributing to the acquired...

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Detalles Bibliográficos
Autores principales: Li, Xinhui, Zhang, Jisheng, Yang, Chengru, Li, Jie, Wang, Jianmin, Huang, Wan, Zeng, Lingyi, Liang, Xushan, Long, Wenzhang, Zhang, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9430841/
https://www.ncbi.nlm.nih.gov/pubmed/35900090
http://dx.doi.org/10.1128/spectrum.00955-22

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