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Mutation in the Two-Component System Regulator YycH Leads to Daptomycin Tolerance in Methicillin-Resistant Staphylococcus aureus upon Evolution with a Population Bottleneck

Adaptive laboratory evolution (ALE) is a useful tool to study the evolution of antibiotic tolerance in bacterial populations under diverse environmental conditions. The role of population bottlenecks in the evolution of tolerance has been investigated in Escherichia coli, but not in a more clinicall...

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Detalles Bibliográficos
Autores principales: Sulaiman, Jordy Evan, Wu, Long, Lam, Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431245/
https://www.ncbi.nlm.nih.gov/pubmed/35913149
http://dx.doi.org/10.1128/spectrum.01687-22

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