Activity of N-Acetylcysteine Alone and in Combination with Colistin against Pseudomonas aeruginosa Biofilms and Transcriptomic Response to N-Acetylcysteine Exposure

Chronic colonization by Pseudomonas aeruginosa is critical in cystic fibrosis (CF) and other chronic lung diseases, contributing to disease progression. Biofilm growth and a propensity to evolve multidrug resistance phenotypes drastically limit the available therapeutic options. In this perspective,...

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Detalles Bibliográficos
Autores principales: Valzano, Felice, Boncompagni, Selene Rebecca, Micieli, Maria, Di Maggio, Tiziana, Di Pilato, Vincenzo, Colombini, Lorenzo, Santoro, Francesco, Pozzi, Gianni, Rossolini, Gian Maria, Pallecchi, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431628/
https://www.ncbi.nlm.nih.gov/pubmed/35735984
http://dx.doi.org/10.1128/spectrum.01006-22

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