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Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2

Senescent cells have long been associated with deleterious effects in aging-related pathologies, although recent studies have uncovered their beneficial roles in certain contexts, such as wound healing. We have found that hepatic stellate cells (HSCs) underwent senescence within 2 days after 2/3 par...

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Detalles Bibliográficos
Autores principales: Cheng, Naiyuan, Kim, Ki-Hyun, Lau, Lester F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431681/
https://www.ncbi.nlm.nih.gov/pubmed/35708907
http://dx.doi.org/10.1172/jci.insight.158207