Cargando…

The epigenetic reader PHF21B modulates murine social memory and synaptic plasticity–related genes

Synaptic dysfunction is a manifestation of several neurobehavioral and neurological disorders. A major therapeutic challenge lies in uncovering the upstream regulatory factors controlling synaptic processes. Plant homeodomain (PHD) finger proteins are epigenetic readers whose dysfunctions are implic...

Descripción completa

Detalles Bibliográficos
Autores principales: Chin, Eunice W.M., Ma, Qi, Ruan, Hongyu, Chin, Camille, Somasundaram, Aditya, Zhang, Chunling, Liu, Chunyu, Lewis, Martin D., White, Melissa, Smith, Tracey L., Battersby, Malcolm, Yao, Wei-Dong, Lu, Xin-Yun, Arap, Wadih, Licinio, Julio, Wong, Ma-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431697/
https://www.ncbi.nlm.nih.gov/pubmed/35866480
http://dx.doi.org/10.1172/jci.insight.158081