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Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience

PURPOSE: This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE. MATERIALS AND METHODS: This prospective study included 10 volunteer subjects...

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Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431979/
https://www.ncbi.nlm.nih.gov/pubmed/36238872
http://dx.doi.org/10.3348/jksr.2020.0133
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description PURPOSE: This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE. MATERIALS AND METHODS: This prospective study included 10 volunteer subjects [mean age, 32.5 years, (range, 23–45 years)] who reported normal activities of daily living and underwent both T2-weighted axial images and MRE of thigh muscles on the same day. A sequence with a motion-encoding gradient was used in the MRE to map the propagating shear waves in the muscle. Elastic properties were quantified as the shear modulus of the following four thigh muscles at rest; the vastus medialis, vastus lateralis, adductor magnus, and biceps femoris. RESULTS: The mean shear modulus was 0.98 ± 0.32 kPa and 1.00 ± 0.33 kPa for the vastus medialis, 1.10 ± 0.46 kPa and 1.07 ± 0.43 kPa for the vastus lateralis, 0.91 ± 0.41 kPa and 0.93 ± 0.47 kPa for the adductor magnus, and 0.99 ± 0.37 kPa and 0.94 ± 0.32 kPa for the biceps femoris, with reader 1 and 2, respectively. No significant difference was observed in the shear modulus based on sex (p < 0.05). Aging consistently showed a statistically significant negative correlation (p < 0.05) with the shear modulus of the thigh muscles, except for the vastus medialis (p = 0.194 for reader 1 and p = 0.355 for reader 2). CONCLUSION: MRE is a quantitative technique used to measure the elastic properties of individual muscles with excellent inter-observer agreement. Age was consistently significantly negatively correlated with the shear stiffness of muscles, except for the vastus medialis.
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spelling pubmed-94319792022-10-12 Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience Taehan Yongsang Uihakhoe Chi Musculoskeletal Imaging PURPOSE: This study aimed to apply MR elastography (MRE) to achieve in vivo evaluation of the elastic properties of thigh muscles and validate the feasibility of quantifying the elasticity of normal thigh muscles using MRE. MATERIALS AND METHODS: This prospective study included 10 volunteer subjects [mean age, 32.5 years, (range, 23–45 years)] who reported normal activities of daily living and underwent both T2-weighted axial images and MRE of thigh muscles on the same day. A sequence with a motion-encoding gradient was used in the MRE to map the propagating shear waves in the muscle. Elastic properties were quantified as the shear modulus of the following four thigh muscles at rest; the vastus medialis, vastus lateralis, adductor magnus, and biceps femoris. RESULTS: The mean shear modulus was 0.98 ± 0.32 kPa and 1.00 ± 0.33 kPa for the vastus medialis, 1.10 ± 0.46 kPa and 1.07 ± 0.43 kPa for the vastus lateralis, 0.91 ± 0.41 kPa and 0.93 ± 0.47 kPa for the adductor magnus, and 0.99 ± 0.37 kPa and 0.94 ± 0.32 kPa for the biceps femoris, with reader 1 and 2, respectively. No significant difference was observed in the shear modulus based on sex (p < 0.05). Aging consistently showed a statistically significant negative correlation (p < 0.05) with the shear modulus of the thigh muscles, except for the vastus medialis (p = 0.194 for reader 1 and p = 0.355 for reader 2). CONCLUSION: MRE is a quantitative technique used to measure the elastic properties of individual muscles with excellent inter-observer agreement. Age was consistently significantly negatively correlated with the shear stiffness of muscles, except for the vastus medialis. The Korean Society of Radiology 2021-11 2021-07-28 /pmc/articles/PMC9431979/ /pubmed/36238872 http://dx.doi.org/10.3348/jksr.2020.0133 Text en Copyrights © 2021 The Korean Society of Radiology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Musculoskeletal Imaging
Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_full Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_fullStr Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_full_unstemmed Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_short Quantification of the Elastic Property of Normal Thigh Muscles Using MR Elastography: Our Initial Experience
title_sort quantification of the elastic property of normal thigh muscles using mr elastography: our initial experience
topic Musculoskeletal Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9431979/
https://www.ncbi.nlm.nih.gov/pubmed/36238872
http://dx.doi.org/10.3348/jksr.2020.0133
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