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Osteoarticular infections in pediatrics()

OBJECTIVE: To collect the most up-to-date information regarding pediatric osteoarticular infections, including the epidemiological and microbiological profiles, diagnosis, and treatment. SOURCE OF DATA: A non-systematic review was performed on the search engines PubMed, SciELO, LILACS, and Google Sc...

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Detalles Bibliográficos
Autores principales: Alvares, Paula Andrade, Mimica, Marcelo Jenné
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432004/
https://www.ncbi.nlm.nih.gov/pubmed/31783013
http://dx.doi.org/10.1016/j.jped.2019.10.005
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author Alvares, Paula Andrade
Mimica, Marcelo Jenné
author_facet Alvares, Paula Andrade
Mimica, Marcelo Jenné
author_sort Alvares, Paula Andrade
collection PubMed
description OBJECTIVE: To collect the most up-to-date information regarding pediatric osteoarticular infections, including the epidemiological and microbiological profiles, diagnosis, and treatment. SOURCE OF DATA: A non-systematic review was performed on the search engines PubMed, SciELO, LILACS, and Google Scholar, using the keywords “bone and joint infection”, “children”, “pediatric”, “osteomyelitis”, “septic arthritis” and “spondylodiscitis” over the last ten years. The most relevant articles were selected by the authors to constitute the database. SYNTHESIS OF DATA: Osteoarticular infections are still a major cause of morbidity in pediatrics. Their main etiology is Staphylococcus aureus, but there has been an increase in the detection of Kingella kingae, especially through molecular methods. Microbiological identification allows treatment direction, while evidence of inflammatory activity assists in treatment follow-up. Imaging tests are especially useful in the initial diagnosis of infections. Empirical treatment should include coverage for the main microorganisms according to the age and clinical conditions of the patient, while considering the local resistance profile. Surgical procedures can be indicated for diagnosis, focus control, and function preservation. Acute complications include sepsis, deep venous thrombosis, and pulmonary embolism. Deaths are rare. Late complications are uncommon but may lead to deformities that compromise motor development. CONCLUSION: A correct and early diagnosis, prompt implementation of adequate antimicrobial therapy, and focus control, when indicated, are critical to a better prognosis.
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spelling pubmed-94320042022-09-08 Osteoarticular infections in pediatrics() Alvares, Paula Andrade Mimica, Marcelo Jenné J Pediatr (Rio J) Review Article OBJECTIVE: To collect the most up-to-date information regarding pediatric osteoarticular infections, including the epidemiological and microbiological profiles, diagnosis, and treatment. SOURCE OF DATA: A non-systematic review was performed on the search engines PubMed, SciELO, LILACS, and Google Scholar, using the keywords “bone and joint infection”, “children”, “pediatric”, “osteomyelitis”, “septic arthritis” and “spondylodiscitis” over the last ten years. The most relevant articles were selected by the authors to constitute the database. SYNTHESIS OF DATA: Osteoarticular infections are still a major cause of morbidity in pediatrics. Their main etiology is Staphylococcus aureus, but there has been an increase in the detection of Kingella kingae, especially through molecular methods. Microbiological identification allows treatment direction, while evidence of inflammatory activity assists in treatment follow-up. Imaging tests are especially useful in the initial diagnosis of infections. Empirical treatment should include coverage for the main microorganisms according to the age and clinical conditions of the patient, while considering the local resistance profile. Surgical procedures can be indicated for diagnosis, focus control, and function preservation. Acute complications include sepsis, deep venous thrombosis, and pulmonary embolism. Deaths are rare. Late complications are uncommon but may lead to deformities that compromise motor development. CONCLUSION: A correct and early diagnosis, prompt implementation of adequate antimicrobial therapy, and focus control, when indicated, are critical to a better prognosis. Elsevier 2019-11-26 /pmc/articles/PMC9432004/ /pubmed/31783013 http://dx.doi.org/10.1016/j.jped.2019.10.005 Text en © 2019 Published by Elsevier Editora Ltda. on behalf of Sociedade Brasileira de Pediatria. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Alvares, Paula Andrade
Mimica, Marcelo Jenné
Osteoarticular infections in pediatrics()
title Osteoarticular infections in pediatrics()
title_full Osteoarticular infections in pediatrics()
title_fullStr Osteoarticular infections in pediatrics()
title_full_unstemmed Osteoarticular infections in pediatrics()
title_short Osteoarticular infections in pediatrics()
title_sort osteoarticular infections in pediatrics()
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432004/
https://www.ncbi.nlm.nih.gov/pubmed/31783013
http://dx.doi.org/10.1016/j.jped.2019.10.005
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