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Opportunistic infections in pediatrics: when to suspect and how to approach()

OBJECTIVES: To describe the characteristics of opportunistic infections in pediatrics regarding their clinical aspects, as well as the diagnostic strategy and treatment. SOURCE OF DATA: Non-systematic review of literature studies in the PubMed database. SYNTHESIS OF DATA: Opportunistic infections ca...

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Autores principales: de Moraes-Pinto, Maria Isabel, Ferrarini, Maria Aparecida Gadiani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432119/
https://www.ncbi.nlm.nih.gov/pubmed/31790645
http://dx.doi.org/10.1016/j.jped.2019.09.008
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author de Moraes-Pinto, Maria Isabel
Ferrarini, Maria Aparecida Gadiani
author_facet de Moraes-Pinto, Maria Isabel
Ferrarini, Maria Aparecida Gadiani
author_sort de Moraes-Pinto, Maria Isabel
collection PubMed
description OBJECTIVES: To describe the characteristics of opportunistic infections in pediatrics regarding their clinical aspects, as well as the diagnostic strategy and treatment. SOURCE OF DATA: Non-systematic review of literature studies in the PubMed database. SYNTHESIS OF DATA: Opportunistic infections caused by non-tuberculous mycobacteria, fungi, Herpesvirae, and infections affecting individuals using immunobiological agents are analyzed. Because these are severe diseases with a rapid evolution, diagnostic suspicion should be early, associated with the patient's clinical assessment and history pointing to opportunistic infections. Whenever possible, samples of secretions, blood, and other fluids and tissues should be collected, with early therapy implementation. CONCLUSIONS: Despite the improved diagnosis of opportunistic infections in recent years, they remain a challenge for pediatricians who are not used to these infections. They should raise the suspicion and start treating the case, but should also resort to specialists in the management of these infections to provide a better outcome for these patients, who still have high mortality.
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spelling pubmed-94321192022-09-08 Opportunistic infections in pediatrics: when to suspect and how to approach() de Moraes-Pinto, Maria Isabel Ferrarini, Maria Aparecida Gadiani J Pediatr (Rio J) Review Article OBJECTIVES: To describe the characteristics of opportunistic infections in pediatrics regarding their clinical aspects, as well as the diagnostic strategy and treatment. SOURCE OF DATA: Non-systematic review of literature studies in the PubMed database. SYNTHESIS OF DATA: Opportunistic infections caused by non-tuberculous mycobacteria, fungi, Herpesvirae, and infections affecting individuals using immunobiological agents are analyzed. Because these are severe diseases with a rapid evolution, diagnostic suspicion should be early, associated with the patient's clinical assessment and history pointing to opportunistic infections. Whenever possible, samples of secretions, blood, and other fluids and tissues should be collected, with early therapy implementation. CONCLUSIONS: Despite the improved diagnosis of opportunistic infections in recent years, they remain a challenge for pediatricians who are not used to these infections. They should raise the suspicion and start treating the case, but should also resort to specialists in the management of these infections to provide a better outcome for these patients, who still have high mortality. Elsevier 2019-11-29 /pmc/articles/PMC9432119/ /pubmed/31790645 http://dx.doi.org/10.1016/j.jped.2019.09.008 Text en © 2019 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
de Moraes-Pinto, Maria Isabel
Ferrarini, Maria Aparecida Gadiani
Opportunistic infections in pediatrics: when to suspect and how to approach()
title Opportunistic infections in pediatrics: when to suspect and how to approach()
title_full Opportunistic infections in pediatrics: when to suspect and how to approach()
title_fullStr Opportunistic infections in pediatrics: when to suspect and how to approach()
title_full_unstemmed Opportunistic infections in pediatrics: when to suspect and how to approach()
title_short Opportunistic infections in pediatrics: when to suspect and how to approach()
title_sort opportunistic infections in pediatrics: when to suspect and how to approach()
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432119/
https://www.ncbi.nlm.nih.gov/pubmed/31790645
http://dx.doi.org/10.1016/j.jped.2019.09.008
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