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펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고

Fentanyl intoxication has occasionally been reported since fentanyl patches became available for medical use. Delayed post-hypoxic leukoencephalopathy is a complication of hypoxia. However, its neuropsychiatric symptoms can be delayed, and it can progress to leukoencephalopathy even after full recov...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432204/
https://www.ncbi.nlm.nih.gov/pubmed/36238168
http://dx.doi.org/10.3348/jksr.2020.81.4.972
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description Fentanyl intoxication has occasionally been reported since fentanyl patches became available for medical use. Delayed post-hypoxic leukoencephalopathy is a complication of hypoxia. However, its neuropsychiatric symptoms can be delayed, and it can progress to leukoencephalopathy even after full recovery from coma due to acute intoxication. Herein, we report a case of fentanyl intoxication in a 65-year-old man who was presented to the hospital because of unconsciousness for 13 hours after using ten fentanyl patches simultaneously. Initial brain CT findings were non-specific. Twenty days later, delayed neuropathologic symptoms manifested, and MRI showed bilaterally symmetrical, heterogeneous, confluent high signal intensities on T2-weighted/fluid attenuated inversion recovery MRI in the cerebral white matter with diffusion restriction. This was followed by rapid exacerbation of neuropathological symptoms with diffuse severe cerebral atrophy over 1 year.
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spelling pubmed-94322042022-10-12 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고 Taehan Yongsang Uihakhoe Chi Neuroradiology & Neurointervention Fentanyl intoxication has occasionally been reported since fentanyl patches became available for medical use. Delayed post-hypoxic leukoencephalopathy is a complication of hypoxia. However, its neuropsychiatric symptoms can be delayed, and it can progress to leukoencephalopathy even after full recovery from coma due to acute intoxication. Herein, we report a case of fentanyl intoxication in a 65-year-old man who was presented to the hospital because of unconsciousness for 13 hours after using ten fentanyl patches simultaneously. Initial brain CT findings were non-specific. Twenty days later, delayed neuropathologic symptoms manifested, and MRI showed bilaterally symmetrical, heterogeneous, confluent high signal intensities on T2-weighted/fluid attenuated inversion recovery MRI in the cerebral white matter with diffusion restriction. This was followed by rapid exacerbation of neuropathological symptoms with diffuse severe cerebral atrophy over 1 year. The Korean Society of Radiology 2020-07 2020-03-17 /pmc/articles/PMC9432204/ /pubmed/36238168 http://dx.doi.org/10.3348/jksr.2020.81.4.972 Text en Copyrights © 2020 The Korean Society of Radiology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Neuroradiology & Neurointervention
펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
title 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
title_full 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
title_fullStr 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
title_full_unstemmed 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
title_short 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
title_sort 펜타닐 첩포 남용으로 인한 지연성 저산소성 백색질뇌증: 증례 보고
topic Neuroradiology & Neurointervention
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432204/
https://www.ncbi.nlm.nih.gov/pubmed/36238168
http://dx.doi.org/10.3348/jksr.2020.81.4.972
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