HIV infected CD4+ T cell clones are more stable than uninfected clones during long-term antiretroviral therapy

Although combination antiretroviral therapy (ART) blocks HIV replication, it is not curative because infected CD4+ T cells that carry intact, infectious proviruses persist. Understanding the behavior of clones of infected T cells is important for understanding the stability of the reservoir; however...

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Detalles Bibliográficos
Autores principales: Guo, Shuang, Luke, Brian T., Henry, Amy R., Darko, Samuel, Brandt, Leah D., Su, Ling, Sun, David, Wells, Daria, Joseph, Kevin W., Demirov, Dimiter, Halvas, Elias K., Douek, Daniel C., Wu, Xiaolin, Mellors, John W., Hughes, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432747/
https://www.ncbi.nlm.nih.gov/pubmed/36044447
http://dx.doi.org/10.1371/journal.ppat.1010726

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