Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania

We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses o...

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Detalles Bibliográficos
Autores principales: Waggle, Kady D., Griffith, Marissa P., Zhu, Lei, Cooper, Vaughn S., Snyder, Daniel J., Srinivasa, Vatsala, Phan, Tung, Wells, Alan, Snyder, Graham M., Van Tyne, Daria, Harrison, Lee H., Marsh, Jane W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432771/
https://www.ncbi.nlm.nih.gov/pubmed/36044529
http://dx.doi.org/10.1371/journal.pone.0272954
Descripción
Sumario:We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.

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