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Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses o...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432771/ https://www.ncbi.nlm.nih.gov/pubmed/36044529 http://dx.doi.org/10.1371/journal.pone.0272954 |
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author | Waggle, Kady D. Griffith, Marissa P. Zhu, Lei Cooper, Vaughn S. Snyder, Daniel J. Srinivasa, Vatsala Phan, Tung Wells, Alan Snyder, Graham M. Van Tyne, Daria Harrison, Lee H. Marsh, Jane W. |
author_facet | Waggle, Kady D. Griffith, Marissa P. Zhu, Lei Cooper, Vaughn S. Snyder, Daniel J. Srinivasa, Vatsala Phan, Tung Wells, Alan Snyder, Graham M. Van Tyne, Daria Harrison, Lee H. Marsh, Jane W. |
author_sort | Waggle, Kady D. |
collection | PubMed |
description | We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination. |
format | Online Article Text |
id | pubmed-9432771 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-94327712022-09-01 Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania Waggle, Kady D. Griffith, Marissa P. Zhu, Lei Cooper, Vaughn S. Snyder, Daniel J. Srinivasa, Vatsala Phan, Tung Wells, Alan Snyder, Graham M. Van Tyne, Daria Harrison, Lee H. Marsh, Jane W. PLoS One Research Article We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination. Public Library of Science 2022-08-31 /pmc/articles/PMC9432771/ /pubmed/36044529 http://dx.doi.org/10.1371/journal.pone.0272954 Text en © 2022 Waggle et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Waggle, Kady D. Griffith, Marissa P. Zhu, Lei Cooper, Vaughn S. Snyder, Daniel J. Srinivasa, Vatsala Phan, Tung Wells, Alan Snyder, Graham M. Van Tyne, Daria Harrison, Lee H. Marsh, Jane W. Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania |
title | Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania |
title_full | Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania |
title_fullStr | Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania |
title_full_unstemmed | Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania |
title_short | Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania |
title_sort | genomic characterization of sars-cov-2 from vaccine breakthrough cases in allegheny county, pennsylvania |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432771/ https://www.ncbi.nlm.nih.gov/pubmed/36044529 http://dx.doi.org/10.1371/journal.pone.0272954 |
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