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Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania

We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses o...

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Autores principales: Waggle, Kady D., Griffith, Marissa P., Zhu, Lei, Cooper, Vaughn S., Snyder, Daniel J., Srinivasa, Vatsala, Phan, Tung, Wells, Alan, Snyder, Graham M., Van Tyne, Daria, Harrison, Lee H., Marsh, Jane W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432771/
https://www.ncbi.nlm.nih.gov/pubmed/36044529
http://dx.doi.org/10.1371/journal.pone.0272954
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author Waggle, Kady D.
Griffith, Marissa P.
Zhu, Lei
Cooper, Vaughn S.
Snyder, Daniel J.
Srinivasa, Vatsala
Phan, Tung
Wells, Alan
Snyder, Graham M.
Van Tyne, Daria
Harrison, Lee H.
Marsh, Jane W.
author_facet Waggle, Kady D.
Griffith, Marissa P.
Zhu, Lei
Cooper, Vaughn S.
Snyder, Daniel J.
Srinivasa, Vatsala
Phan, Tung
Wells, Alan
Snyder, Graham M.
Van Tyne, Daria
Harrison, Lee H.
Marsh, Jane W.
author_sort Waggle, Kady D.
collection PubMed
description We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.
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spelling pubmed-94327712022-09-01 Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania Waggle, Kady D. Griffith, Marissa P. Zhu, Lei Cooper, Vaughn S. Snyder, Daniel J. Srinivasa, Vatsala Phan, Tung Wells, Alan Snyder, Graham M. Van Tyne, Daria Harrison, Lee H. Marsh, Jane W. PLoS One Research Article We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination. Public Library of Science 2022-08-31 /pmc/articles/PMC9432771/ /pubmed/36044529 http://dx.doi.org/10.1371/journal.pone.0272954 Text en © 2022 Waggle et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Waggle, Kady D.
Griffith, Marissa P.
Zhu, Lei
Cooper, Vaughn S.
Snyder, Daniel J.
Srinivasa, Vatsala
Phan, Tung
Wells, Alan
Snyder, Graham M.
Van Tyne, Daria
Harrison, Lee H.
Marsh, Jane W.
Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
title Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
title_full Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
title_fullStr Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
title_full_unstemmed Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
title_short Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania
title_sort genomic characterization of sars-cov-2 from vaccine breakthrough cases in allegheny county, pennsylvania
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432771/
https://www.ncbi.nlm.nih.gov/pubmed/36044529
http://dx.doi.org/10.1371/journal.pone.0272954
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