Successful infusional 5-fluorouracil administration in a patient with vasospastic angina

A 48-year-old female with metastatic colon adenocarcinoma and history of pre-existing coronary vasospasm with ventricular tachycardia (VT) successfully tolerated de novo 5-fluorouracil (5-FU) chemotherapy infusions with prophylactic administration and optimization of anti-spasm medications. 5-FU has...

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Autores principales: Tai, Shannon, Mohananey, Divyanshu, Griffiths, Claire, Johnson, Bradley, Garg, Jalaj, Ridolfi, Timothy J., Lohr, Nicole L., Chakrabarti, Sakti, Brown, Sherry-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432777/
https://www.ncbi.nlm.nih.gov/pubmed/36051246
http://dx.doi.org/10.1016/j.ahjo.2022.100147
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author Tai, Shannon
Mohananey, Divyanshu
Griffiths, Claire
Johnson, Bradley
Garg, Jalaj
Ridolfi, Timothy J.
Lohr, Nicole L.
Chakrabarti, Sakti
Brown, Sherry-Ann
author_facet Tai, Shannon
Mohananey, Divyanshu
Griffiths, Claire
Johnson, Bradley
Garg, Jalaj
Ridolfi, Timothy J.
Lohr, Nicole L.
Chakrabarti, Sakti
Brown, Sherry-Ann
author_sort Tai, Shannon
collection PubMed
description A 48-year-old female with metastatic colon adenocarcinoma and history of pre-existing coronary vasospasm with ventricular tachycardia (VT) successfully tolerated de novo 5-fluorouracil (5-FU) chemotherapy infusions with prophylactic administration and optimization of anti-spasm medications. 5-FU has been reported to produce severe cardiotoxic side effects, including coronary vasospasm, ventricular arrhythmias, and sudden cardiac death, and is not typically reported in individuals with pre-existing coronary vasospasm.
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spelling pubmed-94327772022-08-31 Successful infusional 5-fluorouracil administration in a patient with vasospastic angina Tai, Shannon Mohananey, Divyanshu Griffiths, Claire Johnson, Bradley Garg, Jalaj Ridolfi, Timothy J. Lohr, Nicole L. Chakrabarti, Sakti Brown, Sherry-Ann Am Heart J Plus Article A 48-year-old female with metastatic colon adenocarcinoma and history of pre-existing coronary vasospasm with ventricular tachycardia (VT) successfully tolerated de novo 5-fluorouracil (5-FU) chemotherapy infusions with prophylactic administration and optimization of anti-spasm medications. 5-FU has been reported to produce severe cardiotoxic side effects, including coronary vasospasm, ventricular arrhythmias, and sudden cardiac death, and is not typically reported in individuals with pre-existing coronary vasospasm. 2022-05 2022-05-28 /pmc/articles/PMC9432777/ /pubmed/36051246 http://dx.doi.org/10.1016/j.ahjo.2022.100147 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Article
Tai, Shannon
Mohananey, Divyanshu
Griffiths, Claire
Johnson, Bradley
Garg, Jalaj
Ridolfi, Timothy J.
Lohr, Nicole L.
Chakrabarti, Sakti
Brown, Sherry-Ann
Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
title Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
title_full Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
title_fullStr Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
title_full_unstemmed Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
title_short Successful infusional 5-fluorouracil administration in a patient with vasospastic angina
title_sort successful infusional 5-fluorouracil administration in a patient with vasospastic angina
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432777/
https://www.ncbi.nlm.nih.gov/pubmed/36051246
http://dx.doi.org/10.1016/j.ahjo.2022.100147
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