Rescue of the Congenital Hereditary Endothelial Dystrophy Mouse Model by Adeno-Associated Virus–Mediated Slc4a11 Replacement

PURPOSE: Congenital hereditary endothelial dystrophy (CHED) is a rare condition that manifests at an early age showing corneal edema, increased oxidative stress, mitochondrial dysfunction, and eventually apoptosis of the endothelium due to loss of function of the membrane transport protein SLC4A11....

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Detalles Bibliográficos
Autores principales: Shyam, Rajalekshmy, Ogando, Diego G., Kim, Edward T., Murugan, Subashree, Choi, Moonjung, Bonanno, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432820/
https://www.ncbi.nlm.nih.gov/pubmed/36051248
http://dx.doi.org/10.1016/j.xops.2021.100084

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